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USP7 sustains an active epigenetic program via stabilizing MLL2 and WDR5 in dif…

Wu(Y),Gu(H),Bao(Y),Lin(T),Wang(Z),Gu(D),Shen… Cell Biochem Funct 2022-06-00

...SYK, BTK, PLCG2, PRKCB, MALT1, BCL10, and CARD11) and targets of BCR signaling (MYC and IRF4). In summary, we demonstrat...

Blimp-1 Upregulation by Multiple Ligands via EGFR Transactivation Inhibits Cell…

Lee(H),Huang(DY),Chang(HC),Lin(CY),Ren(WY),D… Front Pharmacol 2022-00-00

...Syk inhibitor can block Blimp-1 gene expression caused by PMA. Reporter assay of Blimp-1 promoter activity further indic...

Expression of dectin-1 and enhanced activation of NALP3 inflammasome are associ…

Feriotti(Claudia),Bazan(Silvia B),Loures(Flá… Front Microbiol 2015-09-21

...Syk kinase phosphorylation and expression of intracellular pro-IL-1β than B10.A cells. These findings led us to investig...

An anti-inflammatory property of Candida albicans β-glucan: Induction of high l…

Smeekens(SP),Gresnigt(MS),Becker(KL),Cheng(S… Cytokine 2015-02-00

...Syk or Raf-1 pathways only marginally reduced C. albicans-induced IL-1Ra production, while blocking of the complement re...

Phosphocholine-containing ligands direct CRP induction of M2 macrophage polariz…

Trial(JoAnn),Cieslik(Katarzyna A),Entman(Mar… Immun Inflamm Dis 2016-09-13

...SYK phosphorylation.,We conclude that CRP with ligands can promote M2 macrophage differentiation to fibroblasts through ...

Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell prec…

Erasmus(M Frank),Matlawska-Wasowska(Ksenia),… Sci Signal 0000-00-00

...Syk. For comparison, we evaluated pre-BCR aggregation mediated by dimeric galectin-1, which has binding sites for carboh...

Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibi…

Suber(J),Zhang(Y),Ye(P),Guo(R),Burks(AW),Kul… Front Immunol 2022-00-00

...SYK and ERK, signal transduction proteins downstream of FcϵRI. Engaging inhibitory cell surface receptors CD300a or Sigl...

Exploring Asthma Mechanism of Belamcanda Chinensis by "Dose-effect Weighted Coe…

Zhang(K),Lv(J),Shen(J),Zhang(N),Gao(X),Wang(… Comb Chem High Throughput Scr… 2025-00-00

...SYK, AKT1, and ALOX5 to be the main key targets, and Fc epsilon RI as the promising signaling pathway. Eight components,...

Population Pharmacokinetics of Mivavotinib (TAK-659), a Dual Spleen Tyrosine Ki…

Li(C),Watson(K),Wang(S),Diderichsen(PM),Gupt… J Clin Pharmacol 2023-00-00

...SYK/FLT3), is under development for the treatment of patients with advanced malignancies. In this analysis, we evaluated...

Genetic and environmental associations of nonspecific chromosomal aberrations.

Hemminki(K),Niazi(Y),Vodickova(L),Vodicka(P)… Mutagenesis 2025-03-15

...SYK, and SEMA6A; a third small group mapped to genes KLF7, SEMA5A and ITGB3 which were related to autistic traits, known...

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