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Network pharmacology-based analysis of the mechanism of Saposhnikovia divaricat…

Li(X),Li(H),Wang(T),Zhao(Y),Shao(Y),Sun(Y),Z… Pharm Biol 2022-12-00

...Syk, PI3K/AKT and MAPK signalling pathways. Saposhnikovia divaricata could inhibit IgE-induced degranulation of mast cel...

CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung infla…

Sung(PS),Yang(SP),Peng(YC),Sun(CP),Tao(MH),H… J Biomed Sci 2022-07-11

...Syk-coupled C-type lectin member 5A (CLEC5A) and TLR2. Blockade of CLEC5A inhibited COVID-19 EVs-induced NETosis, and si...

Longitudinal tracking of subpopulation dynamics and molecular changes during LN…

Rycaj(Kiera),Cho(Eun Jeong),Liu(Xin),Chao(Hs… Oncotarget 0000-00-00

...Syk, GSK3) inhibitors as well as the BCL2 inhibitor that could effectively sensitize the LNCaP-CRPC cells to killing. Of...

Interactive Effect of Combined Intermittent and Sustained Hypoxia and High-Fat …

Mashaqi(S),Laubitz(D),Morales(EJD),De Armond… Nat Sci Sleep 2022-00-00

...Syk (tight junction dysfunction and increased mucosal permeability), while the barrier promoting claudin 4 was downregul...

Anti-Inflammatory Effects and Decreased Formation of Neutrophil Extracellular T…

Saithong(S),Saisorn(W),Tovichayathamrong(P),… Int J Mol Sci 2022-04-27

...SYK, ERK and PKC) was measured using real-time qPCR. The levels of NET products were elevated in the plasma of COVID-19 ...

[Genetic basis of immune response of lymphocyte-like cells in the mucosal immun…

Xin(Liu),Xueying(Song),Xiaoping(Zhang),Yingl… Yi Chuan 2016-01-11

...Syk, Btk and Blnk were not changed significantly, indicating the activation of TCR-like signal transduction pathway afte...

T-independent B-cell effect of agents associated with swine grower-finisher dia…

Barbosa(JA),Yang(CT),Finatto(AN),Cantarelli(… Vet Res Commun 2024-04-00

...syk), tyrosine-protein kinase (lyn), and Tumour Necrosis Factor alpha (TNF-α), and elicited no change in immunoglobulin-...

Network-Based In Silico Analysis of New Combinations of Modern Drug Targets wit…

Assefi(M),Lewandrowski(KU),Lorio(M),Fiorelli… J Pers Med 2023-10-29

...SyK inhibitors like Fos-tamatinib, MAPK inhibitors such as Talmapimod, T-cell inhibitors (Abatacept), IL6 blockers (Toci...

Interactions between Siglec-8 and endogenous sialylated cis ligands restrain ce…

Cao(Y),Rische(CH),Bochner(BS),O'Sullivan(JA) Front Immunol 2023-00-00

...Syk, PI3K, and PLC. These results implicate cis ligands in restraining Siglec-8 function on eosinophils and mast cells a...

Mature tertiary lymphoid structures tumor microenvironment-based risk model to …

Gu(Z),He(C),Cheng(S),Su(Q),Yu(J) Transl Cancer Res 2026-02-28

...SYK, GRB2, LYN, HLA-A, LCK, FYN, PIK3CD, and VAV1. From this, a seven-gene prognostic signature containing CXCL11, CASC8...

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