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Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regul...

Linossi(Edmond M),Chandrashekaran(Indu R),... PLoS One 2014-04-22

...SOCS3. In addition, we identify phosphoTyr317 in Shc-1 as a high-affinity substrate for the SOCS5-SH2 domain and suggest...

Unique transcriptional profile of sustained ligand-activated preconditioning ...

Ashton(Kevin J),Tupicoff(Amanda),Williams-... PLoS One 2014-06-15

...Socs3; putative: Il6, Gadd45g,Rcan1) and transcriptional controllers (Egr2,Egr3, Fos,Hmox1,Nfkbid). Biological themes mo...

The retinol esterifying enzyme LRAT supports cell signaling by retinol-bindin...

Marwarha(Gurdeep),Berry(Daniel C),Croniger... FASEB J 2014-02-26

...SOCS3, an inhibitor of insulin receptor, holo-RBP suppresses insulin responses in STRA6-expressing cells. We have shown ...

SOCS3 dictates the transition of divergent time-phased events in granulocyte ...

Chhabra(Jasmeet Kaur),Chattopadhyay(Brajad... Cell Mol Immunol 2014-08-21

...SOCS3) expression limits the ongoing NF-κB activation and promotes apoptosis; further, we suggest an altered view of how...

SOCS, inflammation, and cancer.

Inagaki-Ohara(Kyoko),Kondo(Taisuke),Ito(Mi... JAKSTAT 2014-06-24

...SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progre...

SOCS3: A novel therapeutic target for cardioprotection.

Yasukawa(Hideo),Nagata(Takanobu),Oba(Toyoh... JAKSTAT 2014-06-24

...SOCS3 is a key determinant of left ventricular remodeling after MI, and SOCS3 may serve as a novel therapeutic target to...

Pattern-recognition receptor signaling regulator mRNA expression in humans an...

Günthner(Roman),Kumar(Vankayala Ramaiah Sa... Int J Mol Sci 2014-03-19

...SOCS3, SHIP, IRAK-M, DOK1, DOK2, SHP1, SHP2, TOLLIP, IRF4, SIKE, NLRX1, ERBIN, CENTB1, and Clec4a2 in human and mouse so...

Epidermal growth factor receptor signaling impairs the antiviral activity of ...

Lupberger(Joachim),Duong(François H T),Fof... Hepatology 2014-02-13

...SOCS3) in the presence of erlotinib and enhanced expression of the IRGs, radical S-adenosyl methionine domain containing...

Hepatitis B virus HBx protein impairs liver regeneration through enhanced exp...

Quétier(Ivan),Brezillon(Nicolas),Duriez(Ma... J Hepatol 2014-03-03

...SOCS3 transcript accumulation and a decrease in ERK1/2 phosphorylation in the livers of HBx transgenic mice. The involve...

[Expression profiles of IL-10, TNF-a, and SOCS3 in placenta of pregnant women...

Cao(Li-qiong),Qu(Guang-di),Wang(Dong-mei) Zhonghua Gan Zang Bing Za Z... 2014-04-07

...SOCS3 protein was significantly more abundant in the control placentas than in the ICP placentas. Furthermore, SOCS3 and...

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