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Functionalized aluminum hydroxide-based self-adjuvanted nanovaccine orchestrate…

Ling(X),Tian(Z),Chen(D),Zhang(Y),Dong(Z),He(… J Control Release 2025-02-10

...Syk and Raf1 signaling pathways and leading to upregulated TNFSF15 and OX40L expression to activate APCs. Following immu...

Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in …

Tullemans(BME),Nagy(M),Sabrkhany(S),Griffioe… Front Cardiovasc Med 2018-00-00

...Syk. Furthermore, pazopanib inhibited GPVI-induced Ca2+ elevation, resulting in reduced exposure of the procoagulant pho...

Curcumenol Inhibits Mast Cells Activation in Ovalbumin-Induced Anaphylaxis Mode…

Kang(YM),Shim(KS),Chae(SW),Bok(SH),Park(DH),… Biomol Ther (Seoul) 2025-07-01

...Syk) in the FcεRI signaling pathway in BMMCs. Furthermore, curcumenol suppressed the activation of Akt, PLCγ1, and mitog...

Synergistic effects of deleting the tyrosine phosphatases Shp1 and Shp2 on mega…

Barré(E),Lourenco-Rodrigues(MD),Zimmermann(L… bioRxiv 2025-10-26

...Syk phosphorylation, associated with reduction GPVI and integrin α2 subunit expression. Reduced Shp1 and Shp2 expression...

Identification of immune-relevant candidate genes in atherosclerosis by WGCNA a…

Cao(Y),Wei(Y),Xue(R),Yang(Y),Sun(W),Dong(W) Medicine (Baltimore) 2025-11-14

...SYK, PTPRC, ITGAL, FGR, and IL10RA) associated with AS, constructed diagnostic models, and predicted potential therapeut...

All-Trans Retinoic Acid Impairs Platelet Function and Thrombus Formation and In…

Luo(Q),Wei(G),Wang(X),Xu(X),Ju(W),Li(Z),Gard… Thromb Haemost 2019-00-00

...Syk and PLCγ2. In addition, ATRA-treated mice displayed significantly impaired hemostasis and arterial thrombus formatio...

Inhibition of Allergic Reactivity through Targeting FcεRI-Bound IgE with Humani…

Zhang(K),Elias(M),Zhang(H),Liu(J),Kepley(C),… J Immunol 2019-00-01

...Syk, Akt, Erk, and p38 MAPK. These studies demonstrate that targeting surface-bound IgE with LARI profoundly suppresses ...

Rapid Characterization of Chemical Components in Edible Mushroom Sparassis cris…

Wang(Z),Liu(J),Zhong(X),Li(J),Wang(X),Ji(L),… Molecules 2019-08-20

...Syk as receptors, followed by the anti-inflammatory activity evaluation for screened hits by intracellular calcium mobil...

Chronic Ly49H Receptor Engagement in vivo Decreases NK Cell Response to Stimula…

Key(PN),Germino(J),Yang(L),Piersma(SJ),Tripa… Front Immunol 2019-00-00

...Syk) at baseline and phosphorylated phospholipase C gamma 2 (p-PLCγ2) at both baseline and following stimulation through...

In-silico discovery of druggable molecular signatures that drive dengue fever t…

Al Noman(M),Latif(MA),Ahmed(MF),Islam(MS),Al… Sci Rep 2025-11-11

...SYK, CYBB, SOCS3, HSPA5, IRF7, NFKB1, IL-6, ISG15, and TNFSF13B) were identified from the selected cell types through di...

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