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Aspartic Proteases and Major Cell Wall Components in Candida albicans Trigger t…

Zawrotniak(M),Bochenska(O),Karkowska-Kuleta(… Front Cell Infect Microbiol 2017-00-00

...Syk, PI3K, and ERK) was also investigated. β-Glucans were found to trigger a ROS-dependent process of NET production wit...

Oroxylin A-induced Trained Immunity Promotes LC3-associated Phagocytosis in Mac…

Yin(L),Bing(Z),Zheng(Y),Pan(Y),Dong(Y),Wang(… Inflammation 2024-12-00

...syk axis to promote LC3-associated phagocytosis (LAP) by trained macrophages, thereby enhancing the ability of these mac...

Efficacy and safety of fostamatinib in refractory immune thrombocytopenia: a me…

Tungjitviboonkun(S),Bumrungratanayos(N),Jitw… Ann Hematol 2024-09-00

...SYK) inhibitor, has emerged as a promising option for refractory ITP. This meta-analysis aims to evaluate the efficacy a...

The bacterial meta-cleavage hydrolase LigY belongs to the amidohydrolase superf…

Kuatsjah(E),Chan(ACK),Kobylarz(MJ),Murphy(ME… J Biol Chem 2017-00-03

...SYK-6 of the bacterium Sphingobium sp. catabolizes lignin-derived biphenyl via a meta-cleavage pathway. In this pathway,...

Using machine learning to dissect host kinases required for Leishmania internal…

Wei(L),Barrie(U),Aloisio(GM),Khuong(FTH),Ara… Mol Biochem Parasitol 2024-00-00

...SYK)), but we also uncovered many novel kinases. Our methods also predicted host kinases necessary for promastigotes to ...

Computational Elucidation of Hub Genes and Pathways Correlated with the Develop…

Tan(CH),Lim(SH),Sim(KS) Biochem Genet 2025-01-30

...SYK, ZEB1, and SELL. Their roles were ascertained by utilizing Gene Ontology keywords and pathway enrichment studies. Ou...

SARS-CoV-2 nucleocapsid protein induces a Mincle-dependent macrophage inflammat…

Tan(RZ),Zhao(WJ),Gao(J),Lan(HY),Liu(J),Wang(… Inflamm Res 2025-04-17

...Syk/NF-κB signaling pathway, leading to damage and inflammation of renal tubular epithelial cells. This was confirmed in...

Mutational landscape induced by chronic exposure to environmental PM10 and PM2.…

Quezada-Maldonado(EM),Cerrato-Izaguirre(D),M… Chemosphere 2024-11-00

...SYK (oncogene) and mutations in NCOR1 (tumor suppressor gene) were prevalent in cells exposed to either PM10 or PM2.5; h...

Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-…

Potuckova(L),Draberova(L),Halova(I),Paulenda… Front Immunol 2018-00-00

...SYK, and phospholipase C. Interestingly, FcεRI-mediated events in BMMCs with PAG-KO were restored upon CSK silencing. BM...

A B-cell receptor-related gene signature predicts survival in mantle cell lymph…

Bomben(R),Ferrero(S),D'Agaro(T),Dal Bo(M),Re… Haematologica 2018-00-00

...SYK), was used to classify the 83 cases (43 B-cell receptorlow and 40 B-cell receptorhigh). The B-cell receptorhigh sign...

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