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Safety and Efficacy of Tyrosine Kinase Inhibitors in Immune Thrombocytopenic Pu…

Ali(MA),Anwar(MY),Aiman(W),Dhanesar(G),Omar(… J Xenobiot 2023-01-28

...Syk) and Bruton's tyrosine kinase (BTK) inhibitors. This review aims to assess the safety and efficacy of TKIs. Methods:...

Restoration of aberrant gene expression of monocytes in systemic lupus erythema…

Nikolakis(D),Garantziotis(P),Sentis(G),Fanou… BMC Genomics 2023-04-18

...SYK kinase inhibitors. Furthermore, according to our network-based drug repurposing approach, an IL-12/23 inhibitor and ...

Sphingobium lignivorans sp. nov., isolated from river sediment downstream of a …

Allemann(MN),Presley(GN),Elkins(JG),Michener… Int J Syst Evol Microbiol 2023-02-00

...SYK-6, with a 100 % 16S rRNA gene sequence similarity. B1D3AT showed 78.1-89.9 % average nucleotide identity and 19.5-22...

The protective effect of p16(INK4a) in oral cavity carcinomas: p16(Ink4A) dampe…

Isayeva(Tatyana),Xu(Jie),Ragin(Camille),Dai(… Mod Pathol 2016-02-24

...Syk might increase MUC1 phosphorylation, leading to the observed decreased MMP1 expression.

Exploration of the mechanism of NORAD activation of TGF-β1/Smad3 through miR-13…

Liu(L),Guo(J),Pang(XL),Shang(WJ),Wang(ZG),Wa… Ren Fail 2023-12-00

...SYK, two luciferase reporters were employed. The renal fibrosis of mice was observed using Masson and PAS staining. The ...

[Prediction of Pathogenesis and Potential Therapeutic Targets for Asthma Based …

Zhi(WB),Liu(Y),Li(Y),Xu(ZR),Jiang(SN),Zhou(J… Zhongguo Yi Xue Ke Xue Yuan X… 2022-12-00

...SYK,VWF,ITGB2,MYD88,COMP,VEGFA,and FCGR2B were identified as the therapeutic targets for asthma.Meanwhile,the biological...

The Inhibitory Effects of Low-Dose Ionizing Radiation in IgE-Mediated Allergic …

Joo(Hae Mi),Kang(Su Jin),Nam(Seon Young),Yan… PLoS One 2016-06-09

...Syk, phospholipase Cγ, and protein kinase C, as well as the intracellular free Ca2+ concentration ([Ca2+]i). The phospho...

Antiatopic dermatitis activity of Lissachatina fulica mucin: Network pharmacolo…

Supiyani(A),Manalu(W),Sutardi(LN),Subangkit(… Turk J Biol 2026-00-00

...SYK, MMP9, AKT1, and ICAM1. The NP analysis identified three major bioactive compounds in LFM-macamide, N-benzyloleamide...

Peripheral blood transcriptomic analysis of patients with rheumatoid arthritis …

Flouda(S),Grigoriou(M),Sentis(G),Grivas(A),M… Arthritis Res Ther 2026-05-06

...Syk and FAK inhibitors are candidate compounds that potentially reverse the transcriptomic signature of RA-ILD progressi...

Targeting NAV2-mediated Wnt/β-catenin signaling in rheumatoid arthritis: curren…

Padmanaban(D),Krishnan(M) Mol Biol Rep 2026-04-28

...SYK-BTK, Notch, NF-κB, and Wnt/β-catenin, play a significant role in disease progression. Among the emerging molecular p...

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