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Inhibition of autoantigen-induced B-cell receptor (BCR) internalization as a th…

Górniak(P),Polak(A),Rams(A),Kupcova(K),Głodk… Cell Death Dis 2026-02-11

...SYK and PI3Kδ inhibitors. Since phenothiazines have well-defined safety and pharmacokinetic profiles, our data provide a...

Gut microbiota dysbiosis and host metabolite-immune crosstalk drives the pathog…

Sun(W),Jin(X),Li(Y),Zhou(M),Liu(X),Wang(H),G… BMC Med 2026-05-28

...SYK) and high-affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) decoupling was observed, correlating with ...

Latent membrane proteins from EBV differentially target cellular pathways to ac…

Ikeda(M),Hayes(CK),Schaller(SJ),Longnecker(R) Blood Adv 2022-00-26

...Syk or cyclin-dependant kinase (CDK)4/6 activity did not effectively inhibit LMP1-mediated MYC lymphomagenesis. Also, in...

A B-cell receptor-related gene signature predicts survival in mantle cell lymph…

Bomben(R),Ferrero(S),D'Agaro(T),Dal Bo(M),Re… Haematologica 2018-00-00

...SYK), was used to classify the 83 cases (43 B-cell receptorlow and 40 B-cell receptorhigh). The B-cell receptorhigh sign...

Computational Elucidation of Hub Genes and Pathways Correlated with the Develop…

Tan(CH),Lim(SH),Sim(KS) Biochem Genet 2025-01-30

...SYK, ZEB1, and SELL. Their roles were ascertained by utilizing Gene Ontology keywords and pathway enrichment studies. Ou...

SARS-CoV-2 nucleocapsid protein induces a Mincle-dependent macrophage inflammat…

Tan(RZ),Zhao(WJ),Gao(J),Lan(HY),Liu(J),Wang(… Inflamm Res 2025-04-17

...Syk/NF-κB signaling pathway, leading to damage and inflammation of renal tubular epithelial cells. This was confirmed in...

Mutational landscape induced by chronic exposure to environmental PM10 and PM2.…

Quezada-Maldonado(EM),Cerrato-Izaguirre(D),M… Chemosphere 2024-11-00

...SYK (oncogene) and mutations in NCOR1 (tumor suppressor gene) were prevalent in cells exposed to either PM10 or PM2.5; h...

Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-…

Potuckova(L),Draberova(L),Halova(I),Paulenda… Front Immunol 2018-00-00

...SYK, and phospholipase C. Interestingly, FcεRI-mediated events in BMMCs with PAG-KO were restored upon CSK silencing. BM...

Immunomodulatory Effects of Extracellular β-Glucan Isolated from the King Oyste…

Kim(YH),Jung(EG),Han(KI),Patnaik(BB),Kwon(HJ… Int J Med Mushrooms 2017-00-00

...Syk-(CARD9/Bcl-10/MALT1) pathway. Our results suggest that PEBG-S could be used as an effective adjuvant or immune enhan...

Ganoderma lucidum spore oil alleviates psychological stress-evoked tumor progre…

Li(DD),Li(ZX),Zhou(YF),Jin(L),Liang(WL),Xu(W… Chin Med 2025-07-14

...SYK-mediated macrophage phagocytosis pathway was confirmed by qPCR, Western blotting, and confocal laser technology. Our...

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