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Anti-atopic dermatitis effects of dictamni cortex: Studies on in vitro and in v…

Chen(Y),Xian(YF),Loo(S),Chan(WY),Liu(L),Lin(… Phytomedicine 2021-02-00

...Syk and PLCγs, suggesting DCE could regulate mast-cell-mediated allergic response. Our experimental results unambiguousl...

Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia.

K Bhanumathy(K),Balagopal(A),Vizeacoumar(FS)… Cancers (Basel) 2021-01-07

...SYK) and pro-oncogenic Abelson tyrosine-protein kinase 1 (ABL1) mutants, are implicated in the pathogenesis and drug res...

Intratumor Heterogeneity Correlates With Reduced Immune Activity and Worse Surv…

Lin(Z),Meng(X),Wen(J),Corral(JM),Andreev(D),… Front Oncol 2020-00-00

...SYK) (p = 0.0011). Highly heterogeneous melanoma tumors are associated with reduced immune cell infiltration and immune ...

Effect of kaempferol on IgE-mediated anaphylaxis in C57BL/6 mice and LAD2 cells.

Cao(J),Li(C),Ma(P),Ding(Y),Gao(J),Jia(Q),Zhu… Phytomedicine 2020-12-00

...Syk, Btk, PLCγ, IP3R, PKC, MAPKs, Akt and NF-κB. Kaempferol could be used as a DJ-1 modulator for preventing MC-mediated...

Transcriptome sequencing identifies genes associated with invasion of ovarian c…

Peng(X),Yu(M),Chen(J) J Int Med Res 2020-09-00

...SYK) were significantly involved in the extracellular matrix-receptor interaction pathway. Downregulated DEGs, such as A...

Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-…

Park(CH),Min(SY),Yu(HW),Kim(K),Kim(S),Lee(HJ… Int J Mol Sci 2020-06-29

...Syk, phospholipase Cγ1, ERK, and JNK) and the expression of high-affinity IgE receptor FcεRIα and cytokines (tumor necro...

Resistance Mutations to BTK Inhibitors Originate From the NF-κB but Not From th…

Smith(CIE),Burger(JA) Front Immunol 2021-00-00

...SYK, BTK, PI3K; still based on the resistance pattern, BTKi therapy only selects GoF alterations in the NF-κB arm, where...

Increased BST-2 expression by HBV infection promotes HBV-associated HCC tumorig…

Zhang(J),Zheng(B),Zhou(X),Zheng(T),Wang(H),W… J Gastrointest Oncol 2021-04-00

...Syk. Here, we observed the higher BST-2 expression in HBV-infected HCC than their paired adjacent tissues and HBV-uninfe...

Identification of a Novel Protein-Based Signature to Improve Prognosis Predicti…

Chu(G),Xu(T),Zhu(G),Liu(S),Niu(H),Zhang(M) Front Mol Biosci 2021-00-00

...SYK, and BRAF. Based on the PRPscore, patients could be divided into two groups with significantly different overall sur...

Complement component C3d-antigen complexes can either augment or inhibit B lymp…

Lee(Y),Haas(KM),Gor(DO),Ding(X),Karp(DR),Gre… J Immunol 2005-12-15

...Syk phosphorylation. Therefore, C3d may enhance or inhibit Ag-specific humoral immune responses through both CD21-depend...

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