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Racial differences in B cell receptor signaling pathway activation.

Longo(DM),Louie(B),Mathi(K),Pos(Z),Wang(E),H… J Transl Med 2012-06-06

...Syk and SFK as well as proteins in the PI3K pathway (S6 and Akt), the MAPK pathways (Erk and p38), and the NF-κB pathway...

Applying ligands profiling using multiple extended electron distribution based …

Dokla(EM),Mahmoud(AH),Elsayed(MS),El-Khatib(… PLoS One 2012-00-00

...syk kinase confirming the recent studies finding of the high activity of diphenyl urea containing compounds against this...

Complement component C3d-antigen complexes can either augment or inhibit B lymp…

Lee(Y),Haas(KM),Gor(DO),Ding(X),Karp(DR),Gre… J Immunol 2005-12-15

...Syk phosphorylation. Therefore, C3d may enhance or inhibit Ag-specific humoral immune responses through both CD21-depend...

A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein in…

Zhu(D),Kepley(CL),Zhang(M),Zhang(K),Saxon(A) Nat Med 2002-05-00

...Syk signaling. The fusion protein also showed increased inhibition of human anti-NP (4-hydroxy-3-nitrophenylacetyl) and ...

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient…

Murphy(MA),Schnall(RG),Venter(DJ),Barnett(L)… Mol Cell Biol 1998-08-00

...Syk/ZAP-70 family of protein kinases.

SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFAT…

Mukai(Tomoyuki),Ishida(Shu),Ishikawa(Remi),Y… J Bone Miner Res 2015-07-14

...SYK) and phospholipase Cγ2 (PLCγ2) phosphorylation, leading to increased nuclear translocation of NFATc1. The heterozygo...

Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin…

Jinawath(N),Vasoontara(C),Jinawath(A),Fang(X… PLoS One 2010-06-18

...SYK, CD97, AIF1, WNK1, SERPINA3, APOD, URP2, STAT5B and RELA (NF-kappaB p65), which were also validated by quantitative ...

Monocytes reprogrammed by 4-PBA potently contribute to the resolution of inflam…

Geng(S),Lu(R),Zhang(Y),Wu(Y),Xie(L),Caldwell… bioRxiv 2023-10-23

...SYK-mTOR signaling. Concurrently, 4-PBA enhanced the expression of resolving mediator CD24 through promoting PPARγ neddy...

Interventions for the management of fatigue in adults with a primary brain tumo…

Day(Julia),Yust-Katz(Shlomit),Cachia(David),… Cochrane Database Syst Rev 2016-07-21

...SYK, DC) independently evaluated search results, extracted data from selected studies and carried out a bias risk assess...

Caspase-1 inhibition by YVAD generates tregs pivoting IL-17 to IL-22 response i…

Patel(D),Challagundla(N),Mandaliya(D),Yadav(… Immunopharmacol Immunotoxicol 2022-06-00

...SYK-1 inhibition in inhibiting inflammasome activation during lung inflammation. In the current manuscript, we explored ...

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