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Immune-mediated hemolytic anemia.

Rosse(WF),Hillmen(P),Schreiber(AD) Hematology Am Soc Hematol Edu… 2004-00-00

...Syk signaling. The role of these receptors in the pathogenesis of hematological diseases due to IgG antibodies is outlin...

Membrane Ig cross-linking regulates phosphatidylinositol 3-kinase in B lymphocy…

Gold(MR),Chan(VW),Turck(CW),DeFranco(AL) J Immunol 1992-04-01

...syk genes, the mIg-associated proteins MB-1 and Ig-beta, phospholipase C-gamma 1 and -gamma 2, as well as many unidentif...

Bannakunin: a dual-target Kunitz inhibitor bridging anticoagulation (FXa/XIIa) …

He(M),He(Y),Feng(X),Li(Z),Lin(T),Yang(J),Luo… Cell Mol Biol Lett 2026-02-22

...Syk/PLCγ2 signalling pathway and the release of Ca2+, TXB2 and ATP. Furthermore, Bannakunin could effectively inhibit AD...

American Joint Committee on Cancer Tumor Staging System Predicts the Outcome an…

Jia(S),Zhu(T),Shi(H),Zong(C),Bao(Y),Wen(X),G… Ophthalmology 2022-00-00

...SYK). Among the 29 patients who developed distant metastasis, we analyzed 2 patterns of metastasis: Eleven patients (38%...

[Berberine induces apoptosis in chronic lymphocytic leukemia B cells by targeti…

Gong(H),Wang(Y),Ma(R),Liu(X),Han(C),Zhang(H)… Xi Bao Yu Fen Zi Mian Yi Xue … 2026-07-00

...Syk), phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT), and apoptosis-related markers Bcl2-associated X prot...

INPP5K limits PtdIns (4,5)P2 accumulation in CD19 microclusters and restrains C…

Moës(B),Mostafa(A),Malempré(R),Renson(O),Pie… Front Immunol 2026-00-00

...SYK) were unchanged or reduced. INPP5K deficiency also increased basal CD19 and BCR microcluster formation, impaired CD1...

Inhibitory effect of fermented Arctium lappa fruit extract on the IgE-mediated …

Yoo(Jae-Myung),Yang(Ju Hye),Yang(Hye Jin),Ch… Int J Mol Med 2016-10-27

...Syk, which are involved in the FcεRI signaling pathway, that of phosphoinositide phospholipase C (PLC)γ1/2 and protein k...

Effects and potential mechanisms of Saposhnikovia divaricata (Turcz.) Schischk.…

Liang(X),Li(X),Sun(S),Zhang(H),Wang(B),Xu(F)… J Ethnopharmacol 2024-01-10

...Syk/PLCγ, MAPK and PI3K/AKT/NF-κB signal pathway to inhibit IgE-dependent cell degranulation. In mice PCA model, both SD...

Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2…

Mishima(S),Sakamoto(M),Kioka(H),Nagata(Y),Su… Front Immunol 2022-00-00

...Syk, and intracellular Ca2+ response) revealed that signaling molecule activation was enhanced in VAMP3 KD cells. We als...

[Screening and validation of therapeutic targets for chronic sinusitis with nas…

Li(T),Sun(CY),Song(ZY),Yang(YJ),Zhang(Y),Son… Zhonghua Er Bi Yan Hou Tou Ji… 2024-07-07

...SYK, PDK2, FGR, PRKCB, ROR1, CAMK1 and GRK6. qPCR showed that the expression of HCK in CRSwNP was significantly higher t...

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