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Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interact…

Zhang(C),Liu(Y),Jiang(J),Chen(C),Duan(Z),Su(… Theranostics 2024-00-00

...Syk. Furthermore, the combination of Vtn knockdown and anti-CD47 antibody effectively enhanced phagocytosis and infiltra...

Natural killer-like B cells are a distinct but infrequent innate immune cell su…

Manickam(C),Upadhyay(AA),Woolley(G),Kroll(KW… PLoS Pathog 2024-05-00

...Syk, and low expression of CD69, α4β7, FcRg, Zap70, and CD3z, findings which were more similar to B cells than NK cells....

Association of DFNA5, SYK, and NELL1 variants along with HPV infection in oral …

Kundu(S),Ramshankar(V),Verma(AK),Thangaraj(S… Tumour Biol 2018-08-00

...SYK and rs1670661 in NELL1 region, involved in genetic susceptibility to tobacco- and HPV-mediated oral oncogenesis. Amo...

Novosphingobium aromaticivorans LigR coordinates transcription of genes involve…

Rodríguez-Castro(L),Myers(KS),Linz(AM),Mette… mSystems 2025-12-17

...SYK-6 transcription factor LigR bound genomic DNA upstream of genes involved in metabolism of multiple aromatic types. W...

Uncovering human kinase substrates in nipah proteome.

Shaji(V),Anil(A),Jabbar(AA),Mahin(A),Rafi(A)… Front Bioinform 2025-00-00

...SYK], with the potential to phosphorylate multiple sites across NiV proteins. Using computational prediction tools, we i...

Diabetic phenotype in mouse and humans reduces the number of microglia around β…

Natunen(T),Martiskainen(H),Marttinen(M),Gabb… Mol Neurodegener 2020-00-10

...Syk-kinase upon ligand-induced activation of Trem2/Dap12 signaling was detected. Finally, characterization of microglial...

TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to …

Hall-Roberts(H),Agarwal(D),Obst(J),Smith(TB)… Alzheimers Res Ther 2020-00-16

...SYK aids phagocytosis, chemotaxis, survival, and changes to microglial activation state. In AD mouse models, knockout (K...

Ras isoforms: signaling specificities in CD40 pathway.

Nair(A),Chakraborty(S),Banerji(LA),Srivastav… Cell Commun Signal 2020-00-06

...syk reduced CD40-induced N-Ras activation but silencing of lyn inhibited H-Ras and K-Ras activation. In CD40 signaling, ...

Astragalus propinquus Schischkin and Panax notoginseng (A&P) compound relieved …

Hui(D),Rui-Zhi(T),Jian-Chun(L),Xia(Z),Dan(W)… J Ethnopharmacol 2020-04-24

...Syk and NF-κB. Notably, A&P down-regulated the M1 macrophage marker iNOS, which may relate to the inhibition of Mincle. ...

Molecular profiling of transformed and metastatic murine squamous carcinoma cel…

Dong(G),Loukinova(E),Chen(Z),Gangi(L),Chantu… Cancer Res 2001-06-15

...syk). Strikingly, 10 of 22 genes in the cluster expressed in metastases have been associated with activation of the nucl...

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