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Distinct functional programming of human fetal and adult monocytes.

Krow-Lucal(Elisabeth R),Kim(Charles C),Bur... Blood 2014-05-12

...SOCS3 to IL-6 receptor in adult monocytes than in fetal monocytes, potentially explaining differences in STAT phosphoryl...

Electrical stimulation induces IL-6 in skeletal muscle through extracellular ...

Bustamante(Mario),Fernández-Verdejo(Rodrig... Am J Physiol Endocrinol Met... 2014-06-04

...SOCS3, a negative regulator of the IL-6 signaling pathway. On the other hand, intracellular calcium chelation or blockad...

Pattern-recognition receptor signaling regulator mRNA expression in humans an...

Günthner(Roman),Kumar(Vankayala Ramaiah Sa... Int J Mol Sci 2014-03-19

...SOCS3, SHIP, IRAK-M, DOK1, DOK2, SHP1, SHP2, TOLLIP, IRF4, SIKE, NLRX1, ERBIN, CENTB1, and Clec4a2 in human and mouse so...

Activation of the JAK-STAT3 pathway is associated with the growth of colorect...

Wei(Xubin),Wang(Gang),Li(Wei),Hu(Xupang),H... Oncol Rep 2014-09-05

...SOCS3 was at a relative low expression level; and ii) AdCN305-cppSOCS3 inhibited the continuous activation of the JAK/ST...

Toll-like receptor and pro-inflammatory cytokine expression during prolonged ...

de Laat(M A),Clement(C K),McGowan(C M),Sil... Vet Immunol Immunopathol 2014-08-11

...SOCS3) expression. Lamellar protein expression of TLR4 and TNF-α, but not IL-6, was increased by the p-EHC, compared to ...

Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via ...

Kim(Jeong-Kook),Kim(Joon-Young),Kim(Han-Jo... PLoS One 2014-07-07

...Socs3. Consistent with this, scoparone decreased phosphorylation and nuclear accumulation of STAT3, but did not reduce p...

Reduced PMA enhances the responsiveness of transfected THP-1 macrophages to p...

Maeß(Marten B),Wittig(Berith),Cignarella(A... J Immunol Methods 2014-03-20

...SOCS3. Further investigation revealed that the cells were classically activated by the differentiation agent phorbol 12-...

Complexity of Interferon-γ Interactions with HSV-1.

Bigley(Nancy J) Front Immunol 2014-06-24

...SOCS3 attenuates cytokine-induced inflammation in the area. A model is presented to unify the effects of IFN-γ, SOCS1, S...

Progression of clinical tuberculosis is associated with a Th2 immune response...

Ashenafi(Senait),Aderaye(Getachew),Bekele(... Clin Immunol 2014-05-16

...SOCS3 (suppressors of cytokine signaling) mRNA and progression of moderate-to-severe disease. Contrary, IL-4, CCL4 and S...

Simvastatin attenuates rhinovirus-induced interferon and CXCL10 secretion fro...

Wickert(Lisa E),Karta(Maya R),Audhya(Anjon... J Leukoc Biol 2014-08-01

...SOCS3 mRNA expression basally or in the presence of RV. Our findings suggest that sim inhibition of the cholesterol bios...

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