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Impaired renal growth hormone JAK/STAT5 signaling in chronic kidney disease.

Wiezel(Debbie),Assadi(Mohammed Hani),Landa... Nephrol Dial Transplant 2014-10-28

...SOCS3) mRNA.,Despite known unaltered circulating GH levels, remnant kidneys of uremic growth retarded juvenile rats show...

Pro-TRH and pro-CRF expression in paraventricular nucleus of small litter-rea...

Aréchiga-Ceballos(F),Alvarez-Salas(E),Mata... J Endocrinol 2014-05-12

...SOCS3, were evaluated in arcuate nucleus, and those of proTRH and proCRF in PVN by real-time PCR. ProTRH expression in a...

IL-23 selectively promotes the metastasis of colorectal carcinoma cells with ...

Zhang(Le),Li(Jun),Li(Li),Zhang(Jie),Wang(X... Carcinogenesis 2014-08-04

...Socs3 expression in which IL-23-induced DNMT-1 was involved. It was elucidated that Socs3 seemed to be one of the import...

NANOG amplifies STAT3 activation and they synergistically induce the naive pl...

Stuart(Hannah T),van Oosten(Anouk L),Radzi... Curr Biol 2014-08-28

...SOCS3. We also discovered NANOG to be limiting for the expression of KLF4, a canonical "Yamanaka" reprogramming factor [...

Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes.

Harder-Lauridsen(N M),Krogh-Madsen(R),Hols... Am J Physiol Endocrinol Met... 2014-05-30

...SOCS3) expression were measured in muscle biopsies. Whole body energy expenditure was measured using indirect calorimetr...

Role of suppressors of cytokine signaling 3 in bone inflammatory responses.

Gao(Anqi),Van Dyke(Thomas E) Front Immunol 2014-06-24

...SOCS3 function in bone remodeling systems implicates SOCS3 as a key signaling molecule in bone cell-mediated inflammator...

FTO contributes to hepatic metabolism regulation through regulation of leptin...

Bravard(Amélie),Vial(Guillaume),Chauvin(Ma... Cell Commun Signal 2014-10-06

...SOCS3 and LepR mRNA levels and with an increased G6P expression. Interestingly, FTO overexpression also induced S727 STA...

Protective role of JAK/STAT signaling against renal fibrosis in mice with uni...

Koike(Kiyomi),Ueda(Seiji),Yamagishi(Sho-ic... Clin Immunol 2014-03-11

...SOCS3 levels in the obstructed kidneys. pSTAT3 levels were further increased in SOCS3(+/-) mice. UUO-induced renal fibro...

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene...

Demokan(Semra),Chuang(Alice Y),Pattani(Kav... Oncol Rep 2014-09-03

...SOCS3 and LHX6] with head and neck squamous cell carcinoma (HNSCC) via a candidate gene approach. After the initial scre...

Differential responses of disease-resistant and disease-susceptible primate m...

Vatter(Heather A),Brinton(Margo A) J Virol 2014-04-08

...SOCS3, a negative regulator of proinflammatory cytokine production. Incubation of macaque cultures with human IL-10 befo...

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