Ohshiro(Taichi),Tomoda(Hiroshi) Expert Opin Ther Pat 2015-12-22

...ACAT2-selective inhibitors, may be potential therapeutics for the treatment of atherosclerosis, homozygous familial hype...

Pedrelli(Matteo),Davoodpour(Padideh),Degir... PLoS One 2015-02-02

...ACAT2 may affect HDL metabolism. The aim of this study was to reveal whether hepatic ACAT2 influences HDL metabolism.,WT...

Matsuda(Daisuke),Ohshiro(Taichi),Ohtawa(Ma... J Antibiot (Tokyo) 2015-03-31

Pyripyropene A (PPPA, 1) of fungal origin, a selective inhibitor of acyl-CoA:cholesterol acyltransferase 2 (ACAT2), prov...

Iqbal(Jahangir),Boutjdir(Mohamed),Rudel(La... J Lipid Res 2015-10-15

...ACAT2 esterifies cholesterol for secretion with chylomicrons. We hypothesized that free cholesterol accumulated during A...

Gordts(Philip L S M),Foley(Erin M),Lawrenc... Cell Metab 2015-09-04

...ACAT2, a key enzyme in cholesterol ester storage; and increased foam cell conversion. Motif analysis of promoters of upr...

Lopez(Adam M),Posey(Kenneth S),Turley(Step... Biochem Biophys Res Commun 2015-05-01

...ACAT2, is the major cholesterol esterifying enzyme in the liver and small intestine (SI). Esterified cholesterol (EC) ca...

Manor(Meghan L),Cleveland(Beth M),Weber(Gr... Comp Biochem Physiol B Bioc... 2015-07-07

...acat2 had higher expression in fish fed higher rations. On the other hand, sexual maturation affected gene expression ac...

Rogers(Maximillian A),Liu(Jay),Song(Bao-Li... J Steroid Biochem Mol Biol 2015-08-11

...ACAT2. Both are allosteric enzymes that can be activated by a variety of sterols. In addition to cholesterol, other ster...

Lei(Lin),Liu(Yuwei),Wang(Xiaobo),Jiao(Rui)... J Agric Food Chem 2015-09-14

...ACAT2), microsomal triacylglycerol transport protein (MTP), and ATP binding cassette transporter 5 (ABCG5), whereas it u...

Yap(Chui Sun),Sinha(Rohit Anthony),Ota(Sho... Biochem Biophys Res Commun 2014-02-14

...ACAT2). CDX2, a known positive regulator of hepatocyte differentiation, was regulated by miR-181d and directly activated...