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High frequency of genes' promoter methylation, but lack of BRAF V600E mutatio...

Naghibalhossaini(Fakhraddin),Hosseini(Hami... Pathol Oncol Res 2012-04-16

...APC2, p14ARF, and ECAD in colorectal carcinogenesis and their association with the mutational status of BRAF and KRAS am...

lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster th...

Nagy(Olga),Pál(Margit),Udvardy(Andor),Shir... Cell Div 2012-10-02

...Apc2, and they together form a binding site for Vihar, the E2-C type ubiquitin conjugating enzyme. Despite being conserv...

Directional neuronal migration is impaired in mice lacking adenomatous polypo...

Shintani(Takafumi),Takeuchi(Yasushi),Fujik... J Neurosci 2012-07-06

...APC2) is a family member of APC and mainly expressed in the nervous system. We previously reported that APC2 plays a cri...

Cortical localization of APC2 plays a role in actin organization but not in W...

Zhou(Meng-Ning),Kunttas-Tatli(Ezgi),Zimmer... J Cell Sci 2011-09-23

...APC2 molecules. To test the function of the cortical localization of APC2, we asked whether an APC2 protein deleted for ...

[Methylation profiling of the cell cycle regulating genes in placenta of huma...

Kashevarova(A A),Tolmacheva(E N),Sazhenova... Mol Biol (Mosk) 2011-07-08

...APC2, BRACA2, DCC, GRLF1, RB1, TP73, TSPYL2, VHL) as well as genes, participating in chromosome segregation regulation (...

Cigarette smoke suppresses the ubiquitin-dependent degradation of OLC1.

Zhang(Xiaojing),Xiao(Ting),Cheng(Shujun),T... Biochem Biophys Res Commun 2011-07-19

...APC2 was impaired. These results demonstrate that CSC regulates OLC1 expression in lung cancer cells by compromising its...

[Effect of recombinant pEGFP-N3-APC vectors carrying various APC functional d...

Lu(Liang),Huo(Jirong),Liu(Jia),Wu(Jie),Wan... Zhong Nan Da Xue Xue Bao Yi... 2011-06-01

...APC2 and pEGFP-N3-APC3, and was distinctly affected after being transfected with pEGFP-N3-APC4 and pEGFP-N3-APC5, especi...

Young-Burgess classification of pelvic ring fractures: does it predict mortal...

Manson(Theodore),O'Toole(Robert V),Whitney... J Orthop Trauma 2011-01-13

...APC2) and 3 (APC3) fractures had higher transfusion requirements than did lateral compression Type 1 (LC1), anteroposter...

Directed microtubule growth, +TIPs, and kinesin-2 are required for uniform mi...

Mattie(Floyd J),Stackpole(Megan M),Stone(M... Curr Biol 2011-04-04

...Apc2-GFP and Apc-RFP to branch points suggests that these proteins work together at dendrite branches. The functional im...

FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phas...

Wen(Hsiang),Kim(Namhun),Fuentes(Ernesto J)... Cell Cycle 2011-03-23

...APC2 levels. However, free APC2 is decreased, inhibiting cell proliferation. Finally, FACS analysis of cell populations ...

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