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World first hybrid neuroendocrine cell line sharing properties of NET G3 and ...

Rogoll(D),Landwehr(LS),Schreiner(J),Hartra... Eur J Endocrinol 2025-08-29

...DAXX, ATRX, mTOR, PTEN, TP53, and RB1. The successful in vivo engraftment rate was high (4/5). The MS-18 cell line is th...

Alternative Lengthening of Telomeres: A Prognostic Paradox in Cancer.

Sung(JY) Cells 2025-10-17

...DAXX, while enabling ALT, further amplifies chromatin fragility, and ALT-mediated instability may paradoxically enhance ...

ATR promotes genome instability via CENP-A eviction from centromeres under re...

Ostapenko(D),Li(H),Trier(I),Shamby(R),Zago... bioRxiv 2025-10-20

...DAXX or ATRX, is necessary for nucleolar CENP-A localization. Importantly, ATR-dependent CENP-A eviction endures after c...

Alternative lengthening of telomeres and loss of ATRX are frequent events in ...

Lee(Jen-Chieh),Jeng(Yung-Ming),Liau(Jau-Yu... Mod Pathol 2016-05-04

...DAXX immunostaining, respectively. Remarkably, all cases with loss of either ATRX or DAXX expression had alternative len...

Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendoc...

Capurso(Gabriele),Archibugi(Livia),Delle F... J Hepatobiliary Pancreat Sc... 2016-05-09

...DAXX, remains uncertain. The present paper reviews the main molecular changes occurring in PNETs and how they might be l...

The Role of Chemotherapy in Well-Differentiated Gastroenteropancreatic Neuroe...

Strosberg(Jonathan),Goldman(Jamie),Costa(F... Front Horm Res 2016-06-20

...DAXX/ATRX, are associated with response to chemotherapy.

TERT promoter mutations are frequent and show association with MED12 mutation...

Yoshida(Masayuki),Ogawa(Reiko),Yoshida(Hir... Br J Cancer 2016-01-28

...DAXX, in a total of 104 phyllodes tumors and fibroadenomas.,Sequencing analyses showed that TERT promoter mutations were...

Adaption by Rewiring Epigenetic Landscapes.

Liu(Yifei),Xiao(Andrew) Cell Stem Cell 2016-06-07

...Daxx/Atrx repress transposons in ESCs devoid of 5mC, demonstrating dynamic reorganization of epigenetic networks and cro...

The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypometh...

He(Quanyuan),Kim(Hyeung),Huang(Rui),Lu(Wei... Cell Stem Cell 2016-06-06

...Daxx and Atrx. Using genome-wide binding and transcriptome analysis, we found that Daxx and Atrx have distinct chromatin...

Molecular cloning and expression analysis of an apoptosis-associated gene Dax...

Qi(Lin),Xiang(Zhiming) Fish Shellfish Immunol 2016-02-22

...Daxx is 2,151bp long and encodes a putative protein of 716 amino acids containing Daxx domain. Though quantitative PCR a...

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