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miR-24 regulates apoptosis by targeting the open reading frame (ORF) region o...

Qin(Wenming),Shi(Yi),Zhao(Botao),Yao(Cheng... PLoS One 2010-09-30

...FAF1) by binding to its amino acid coding sequence (CDS) region, thereby regulating apoptosis in DU-145 cells. This resu...

A compendium of myeloma-associated chromosomal copy number abnormalities and ...

Walker(Brian A),Leone(Paola E),Chiecchio(L... Blood 2010-11-05

...FAF1, CDKN2C), 1q (ANP32E), and 17p (TP53). In addition, we identified common homozygously deleted genes that have funct...

Altered microRNA expression profile with miR-146a upregulation in CD4+ T cell...

Li(Jingyi),Wan(Ying),Guo(Qiuye),Zou(Liyun)... Arthritis Res Ther 2010-11-24

...FAF1) as a miR-146a-regulated gene, which was critically involved in modulating T cell apoptosis.,We have detected incre...

Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiqui...

Besche(Henrike C),Haas(Wilhelm),Gygi(Steve... Biochemistry 2010-04-05

...FAF1, all of which contain ubiquitin-binding motifs. These complexes were isolated with ubiquitin conjugates bound and w...

Negative feedback regulation of Aurora-A via phosphorylation of Fas-associate...

Jang(Moon-Sun),Sul(Jee-Won),Choi(Byung-Jun... J Biol Chem 2009-01-22

...FAF1 mutant mimicking phosphorylation at Ser-289 and Ser-291 (FAF1 DD), but not phosphorylation-deficient FAF1 (FAF1 AA)...

Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated...

Altomare(Deborah A),Menges(Craig W),Pei(Ji... Proc Natl Acad Sci U S A 2009-04-01

...Faf1 and down-regulation of Faf1 protein in a series of MMs from Arf (+/-) mice, and we then showed that Faf1 regulates ...

FAS-associated factor 1 (FAF1): diverse functions and implications for oncoge...

Menges(Craig W),Altomare(Deborah A),Testa(... Cell Cycle 2009-10-27

...FAF1, is an evolutionarily conserved protein that has several protein interaction domains. Although FAF1 was initially i...

Uniparental disomies, homozygous deletions, amplifications, and target genes ...

Beà(Sílvia),Salaverria(Itziar),Armengol(Ll... Blood 2009-05-01

...FAF1, MAP2, SP100, MOBKL2B, ZNF280A, and PRAME). Gene amplification coupled with overexpression was identified in 35 dif...

Fas-associated factor (FAF1) is required for the early cleavage-stages of mou...

Adham(Ibrahim M),Khulan(Janchiv),Held(Tors... Mol Hum Reprod 2008-07-15

...Faf1 locus. The mutation disrupts the Faf1 and leads to lethality of the Faf1(GT/GT) embryos near the 2-cell stage. Anal...

Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent ...

De Zio(D),Ferraro(E),D'Amelio(M),Simoni(V)... Cell Mol Life Sci 2008-07-29

...Faf1 in developing brain, we used cDNA over-expression and mRNA down-regulation experiments to modulate Faf1 expression ...

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