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D'Mello(B),Rivera(D),Rehal(S),Pollock-Tahi... Sci Rep 2026-04-17

...JAK2 in IECs remains poorly understood. To investigate the in vivo role of epithelial JAK2, we generated mice with IEC-s...

Morath(O),Wolfrum(T),Crodel(C),Hochhaus(A)... J Thromb Haemost 2026-08-00

...JAK2 mutation than in JAK2-negative patients. Cytoreductive therapy showed no significant impact on RNA expression. Subt...

Wei(M),Han(W),Wu(J),Li(Z),Tian(M),Xu(J),Ch... Drug Deliv Transl Res 2026-04-19

...JAK2-STAT3 and expression of inflammatory cytokines. Additionally, this study was conducted to further verify the target...

Su(T),Wang(Z),Wu(Y),Li(Q),Tian(L),Li(X),Zh... Int J Biol Sci None

...Jak2 and Stat3, leading to the enhanced Jak2/Stat3 complex formation and subsquently promoting phosphorylation of Stat3....

Liu(C),Gao(Y) AIMS Neurosci None

...JAK2, STAT3, phosphorylated JAK2, phosphorylated STAT3, and cleaved caspase-3 using western blot analysis. Interaction t...

Ahmad(CM),Kastle(RA),Zargarian(L),Sawalha(... Cureus 2026-03-00

...JAK2-positive PV diagnosed in 2020 who progressed to MF in 2024 and developed AML later that year. Cytogenetic analysis ...

Luo(H),Chen(B),Zhang(X) Front Immunol None

...JAK2 inhibitor, in the treatment of patients with Vogt-Koyanagi-Harada (VKH) disease. The study was designed as a prospe...

Yoon(SY),Yoon(SS),Yang(DH),Lee(GW),Sohn(SK... Ther Adv Hematol None

...JAK2 V617F mutations. Ropeginterferon alfa-2b effectively reduces both hematologic parameters and JAK2 allele burden, bu...

Yang(Y),Zhang(Y),Feng(X),Gao(F),Ma(Y),Yang(S) J Hepatocell Carcinoma None

...JAK2/STAT3 signaling. The JAK2/STAT3 inhibitor AG490 was included as a pharmacological reference. PBPs were identified a...

Zhao(CL),Zhang(Y),Guo(JK),Wang(J),Wang(CY)... Autoimmunity 2026-12-31

...JAK2-STAT3 signaling cascade to orchestrate pro-inflammatory cytokine production. Overall, this study reveals novel mole...