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MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human meth...

Lo(Ting-Fang),Tsai(Wei-Chung),Chen(Shui-Tein) PLoS One 2014-05-12

...MAT2A, encode 2 distinct catalytic MAT isoforms. A third gene, MAT2B, encodes a MAT2A regulatory subunit. In hepatocellu...

Expression of methionine adenosyltransferase 2A in renal cell carcinomas and ...

Wang(Xuliang),Guo(Xiaoqiang),Yu(Wenshui),L... BMC Cancer 2014-11-06

...MAT2A in several kinds of cancers such as liver and colon cancers. But the relationship of MAT2A between renal cell carc...

Metabolomic analysis reveals metabolic changes caused by bisphenol A in rats.

Chen(Minjian),Zhou(Kun),Chen(Xiaojiao),Qia... Toxicol Sci 2014-11-10

...Mat2a). Hepatic S-adenosylmethionine (SAMe) was also analyzed. A total of 199 metabolites were profiled. Statistical ana...

Inhibition of proteolysis in histiotrophic nutrition pathways alters DNA meth...

Sant(Karilyn E),Dolinoy(Dana C),Nahar(Muna... J Nutr Biochem 2014-02-06

...Mat2a protein levels and inhibited Mat2a specific activity, all of which produced a significant 52% reduction of SAM in ...

Pleiotropic effects of methionine adenosyltransferases deregulation as determ...

Frau(Maddalena),Feo(Francesco),Pascale(Ros... J Hepatol 2014-06-02

...MAT2A, encoding MATII isozyme, known as MAT1A:MAT2A switch, occurs in hepatocellular carcinoma (HCC). Being inhibited by...

Structure and function study of the complex that synthesizes S-adenosylmethio...

Murray(Ben),Antonyuk(Svetlana V),Marina(Al... IUCrJ 2014-07-30

...mat2A and mat2B, which encode MAT enzymes. mat2A and mat2B transcribe MATα2 and MATβ enzyme subunits, respectively, with...

2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of ...

Sviripa(Vitaliy M),Zhang(Wen),Balia(Andrii... J Med Chem 2014-10-21

Inhibition of the catalytic subunit of the heterodimeric methionine S-adenosyl transferase-2 (MAT2A) with fluorinated N,...

Associations between maternal genotypes and metabolites implicated in congeni...

Chowdhury(Shimul),Hobbs(Charlotte A),MacLe... Mol Genet Metab 2013-03-27

...MAT2A) gene that were associated with methionine levels. Three SNPs in tRNA aspartic acid methyltransferase 1 (TRDMT1) g...

S-adenosylmethionine in liver health, injury, and cancer.

Lu(Shelly C),Mato(José M) Physiol Rev 2013-01-11

...MAT2A that is expressed by all extrahepatic tissues, encode MAT. Patients with chronic liver disease have reduced MAT ac...

Transcriptional signatures mediated by acetylation overlap with early-stage A...

Vadnal(J),Houston(S),Bhatta(S),Freeman(E),... Exp Brain Res 2013-06-06

...Mat2a), and 5-methyltetrahydrofolate homocysteine reductase (Mtrr) overlapped with genes altered in early-stage AD in gr...

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