Ozek(Ceren),Kanoski(Scott E),Zhang(Zhong-Y... J Biol Chem 2015-01-20

...Ptpn1(-/-) mice exhibit enhanced TrkB phosphorylation, and Ptpn1(-/-) mice are hypersensitive to central BDNF-induced in...

Balaramnavar(Vishal M),Srivastava(Rohit),R... Eur J Med Chem 2015-08-19

...PTPN1, Akt2, AMPK and PPAR-α. Western blot analysis of both skeletal muscle and liver demonstrated that proteins and int...

St-Germain(Jonathan R),Taylor(Paul),Zhang(... Proteomics 2015-09-14

...PTPN1. Knockdown of PTPN1 or the related enzyme PTPN2 by RNAi resulted in ligand-independent activation of FGFR3. Modula...

Quaio(Caio Robledo D'Angioli Costa),de Alm... Clinics (Sao Paulo) 2014-05-02

...PTPN1, SOS1, RAF1, KRAS, SHOC2 and BRAF.,The most frequent tegumentary alterations were xeroderma (46%), photosensitivit...

Ovsyannikova(Inna G),White(Sarah J),Larrab... Vaccine 2014-08-14

...PTPN1/LEPR/STAT3 genes associated with peripheral blood TREC levels (p<0.05). Heterozygosity of the synonymous variant r...

Santiago(Jose A),Potashkin(Judith A) Mov Disord 2014-12-03

...ptpn1 as a potential biomarker for PSP. Assessment of biomarker performance revealed that ptpn1 could be used to disting...

Gunawardana(Jay),Chan(Fong Chun),Telenius(... Nat Genet 2014-05-19

...PTPN1 gene. Mutations were found in 6 of 30 (20%) Hodgkin lymphoma cases, in 6 of 9 (67%) Hodgkin lymphoma-derived cell ...

Phillips(Ryan M),Bair(Eric),Lawrence(David... Anal Chem 2014-04-22

...PTPN1 and PTPN2 obeyed Michaelis-Menten kinetics, with KM values of 770 ± 250 and 290 ± 54 nM, respectively. Dose-respon...

Radhakrishnan(Vijayababu M),Kojs(Pawel),Yo... PLoS One 2014-12-03

...PTPN1 tyrosine phosphatases to increase its activity and lead to dephosphorylation of pTyr(421)-CTTN. PTPN1 inhibition e...

Pinto-Leite(Rosário),Carreira(Isabel),Melo... Tumour Biol 2014-06-24

...PTPN1) were coincident across all cell lines. Although some significant heterogeneity and complexity were detected betwe...