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SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML.

Fasci(Domenico),Anania(Veronica G),Lill(Je... Sci Signal 2016-04-04

...SUMO1 and SUMO2) to promote PML ubiquitylation mediated by the ubiquitin E3 ligase RNF4 and reorganization of PML nuclea...

SUMO1 depletion prevents lipid droplet accumulation and HCV replication.

Akil(Abdellah),Wedeh(Ghaith),Zahid Mustafa... Arch Virol 2016-05-17

...SUMO1 is upregulated in Huh7.5 infected cells. Reciprocally, SUMO1 was found to regulate the expression of viral core pr...

Systematically identify key genes in inflammatory and non-inflammatory breast...

Chai(Fan),Liang(Yan),Zhang(Fan),Wang(Mingh... Gene 2016-03-17

...SUMO1, COL1A1, FYN, CAV1, COL5A1 and MMP2 to be the key genes for breast cancer. Interestingly, PDGFRβ was found to be t...

Plasma SUMO1 Protein is Elevated in Alzheimer's Disease.

Cho(Sun-Jung),Yun(Sang-Moon),Lee(Dae-hoon)... J Alzheimers Dis 2016-07-06

...SUMO1 was significantly increased in dementia patients, as compared to control groups. The levels of SUMO1 correlated to...

Regulation of SUMO2 target proteins by the proteasome in human cells exposed ...

Bursomanno(Sara),McGouran(Joanna F),Kessle... J Proteome Res 2016-03-07

...SUMO1, could be regulated by the ubiquitin-mediated proteasome system. Hence, we set out to understand the role of the p...

Comparative ultrastructure of CRM1-Nucleolar bodies (CNoBs), Intranucleolar b...

Souquere(Sylvie),Weil(Dominique),Pierron(G... Nucleus 2016-06-17

...SUMO1 and SUMO-2/3 as strongly as PML bodies. In contrast, the smallest CRM1-labeled CNoBs are vitreous, preferentially ...

Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex.

Sakin(Volkan),Richter(Sebastian M),Hsiao(H... J Biol Chem 2016-01-19

...SUMO1/Ubc9 localizes at cytoplasmic nuclear pore complex (NPC) filaments and is a docking site in nucleocytoplasmic tran...

Prokaryotic expression and mechanism of action of α-helical antimicrobial pep...

Yi(Tonghui),Sun(Shiyu),Huang(Yibing),Chen(... BMC Biotechnol 2016-03-10

...SUMO1/2/3/4 with A20L to construct expression plasmids. Ub-A20L and SUMO1/2/34 gene sequences were inserted into the pHU...

Computational genomic analysis of PARK7 interactome reveals high BBS1 gene ex...

Vavougios(Georgios D),Solenov(Evgeniy I),H... Am J Physiol Lung Cell Mol ... 2016-01-08

...SUMO1, UBC3, KIAA0101, HDAC2, DAXX, RBBP4, BBS1, NONO, RBBP7, HTRA2, and STUB1 were significantly overexpressed whereas ...

A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy S...

Ritho(Joan),Arold(Stefan T),Yeh(Edward T H... Cell Rep 2016-05-09

...SUMO1 modification of LKB1, despite a global reduction in both SUMO1 and SUMO2/3 conjugates. During metabolic stress, SU...

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