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Silencing of miRNA-148a by hypermethylation activates the integrin-mediated sig…

Li(Hsin-Pai),Huang(Hsin-Yi),Lai(Yi-Ru),Huang… Oncotarget 2015-08-06

...VAV2, WASL and ROCK1. Biochemical and functional assays provided supporting evidence that these 3 genes are the downstre...

Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to con…

Havel(L S),Kline(E R),Salgueiro(A M),Marcus(… Oncogene 2015-06-22

...VAV2, as having the greatest loss of phosphorylation owing to vimentin depletion. Since VAV2 serves as a GEF for the sma...

Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic…

Zhu(Shuyong),Zhao(Chengjiang),Wu(Yingying),Y… Nat Neurosci 2015-10-21

...Vav2 is required for DAT cell surface expression and transporter activity modulated by glial cell line-derived neurotrop...

Differential Gene Expression of the Proto-oncogene VAV3 and the Transcript Vari…

Trenkle(Thomas),Hakim(Samer G),Jacobsen(Hans… Anticancer Res 2015-08-06

...VAV2 and VAV3 have been identified as important molecules in tumorigenesis, tumor growth and cell migration. In addition...

Contribution of NADPH oxidase to membrane CD38 internalization and activation i…

Xu(Ming),Li(Xiao-Xue),Ritter(Joseph K),Abais… PLoS One 2014-03-03

...Vav2 or administration of exogenous O2·- significantly increased CD38 internalization in CAMs. Lastly, ET-1 was found to...

The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotio…

Menacho-Márquez(Mauricio),García-Escudero(Ra… PLoS Biol 2014-02-11

...Vav2 and Vav3 favor cooperatively the initiation and promotion phases of skin tumors. Transcriptomal profiling and signa...

Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and…

Jones(Matthew C),Machida(Kazuya),Mayer(Bruce… Mol Biol Cell 2014-01-17

...Vav2 activation downstream of integrin engagement and epidermal growth factor (EGF) stimulation. In turn, Vav2 regulates...

MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma…

Wang(Ruizhi),Zhao(Na),Li(Siwen),Fang(Jian-Ho… Hepatology 2014-01-16

...VAV2 and CDC42 expression, which stimulated VAV2/Rac1/CDC42 signaling and lamellipodia formation and thereby facilitated...

Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell …

Salin-Cantegrel(Adèle),Shekarabi(Masoud),Ras… PLoS One 2014-01-10

...Vav2 as a candidate partner for KCC3. KCC3/Vav2 physical interaction was confirmed using GST-pull down assays and immuno...

Fer protein-tyrosine kinase promotes lung adenocarcinoma cell invasion and tumo…

Ahn(Joseph),Truesdell(Peter),Meens(Jalna),Ka… Mol Cancer Res 2014-04-15

...Vav2 tyrosine phosphorylation that was correlated with direct Fer-mediated phosphorylation of Vav2 on tyrosine-172, whic...

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