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Free fatty acid palmitate impairs the vitality and function of cultured human...

Oberbach(Andreas),Schlichting(Nadine),Hein... PLoS One 2013-01-10

...SOCS3 increased cell proliferation and antioxidant capacity; (iv) further downstream JAK/STAT3 signaling cascade the inh...

Defining an EPOR- regulated transcriptome for primary progenitors, including ...

Singh(Seema),Dev(Arvind),Verma(Rakesh),Pra... PLoS One 2013-03-26

...Socs3 plus Socs2 but also Spred2, Spred1 and Eaf1 were EPO-induced as negative-feedback components. Socs2, plus five add...

G-CSF-treated donor CD4+ T cells attenuate acute GVHD through a reduction in ...

Joo(Young-Don),Lee(Won-Sik),Won(Hae-Jeong)... Cytokine 2013-02-01

...SOCS3) expression in G-CSF-treated donor CD4(+) T cells was much higher than that in control CD4(+) T cells. Our results...

Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes s...

Uto-Konomi(Ayako),Miyauchi(Kosuke),Ozaki(N... PLoS One 2013-04-02

...Socs3 (Socs3 cKO) caused severe skin inflammation with hyper-production of IgE, epidermal hyperplasia, and S100A8/9 expr...

Maternal immune activation alters behavior in adult offspring, with subtle ch...

Connor(Caroline M),Dincer(Aslihan),Straubh... Schizophr Res 2013-01-18

...Socs3), H3K4me3 was sensitive to activation of cytokine signaling in primary cultures from fetal forebrain but adult cor...

The effect of chronic immobilization stress on leptin signaling in the ovarie...

Larco(Darwin O),Cruthirds(Danette F),Weise... Endocrine 2013-05-29

...SOCS3), which is an inhibitor of leptin signaling. Chronic immobilization stress blunted the E2-induced increase in Ob-R...

Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia t...

Zhang(Xue),Zhang(Yun),Tao(Bo),Wang(Di),Che... FASEB J 2013-01-29

...SOCS3-mediated degradation of TYK2. Together, we define a novel role for Gab2 in mediating mucin gene expression and GCH...

Maternal high-fat diet induces obesity and adrenal and thyroid dysfunction in...

Franco(J G),Fernandes(T P),Rocha(C P D),Ca... J Physiol 2013-03-25

...SOCS3 (-55%, P < 0.05) content in the arcuate nucleus, suggesting leptin resistance. HF offspring also had higher adrena...

Reduced Socs3 expression in adipose tissue protects female mice against obesi...

Palanivel(R),Fullerton(M D),Galic(S),Honey... Diabetologia 2013-02-26

...Socs3 floxed (wild-type, WT) and Socs3 aP2 (also known as Fabp4)-Cre null (Socs3 AKO) mice. Mice were maintained on eith...

SOCS1 gene transfer accelerates the transition to heart failure through the i...

Cittadini(Antonio),Monti(Maria Gaia),Iacca... Cardiovasc Res 2013-04-25

...SOCS3 was upregulated during the hypertrophic phase, SOCS1 transcript levels increased significantly between 15 and 20 w...

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