Lu(Ming),Hu(Xi-Han),Li(Qin),Xiong(Ying),Hu... J Mol Cell Biol 2014-09-03

...ACAT2 is abundantly expressed in intestine and fetal liver. Our previous studies have shown that ACAT2 is induced in cer...

Jiao(Rui),Chen(Jingnan),Peng(Cheng),Liang(... J Agric Food Chem 2014-06-23

...ACAT2) as well as microsomal triacylglycerol transport protein (MTP). It was therefore concluded that the plasma cholest...

Pramfalk(Camilla),Melhuish(Tiffany A),Wott... J Lipid Res 2014-12-09

Acat2 [gene name: sterol O-acyltransferase 2 (SOAT2)] esterifies cholesterol in enterocytes and hepatocytes. This study ...

Shi(Yinghua),Guo(Rui),Wang(Xianke),Yuan(De... PLoS One 2014-09-29

...Acat2, Cyp7a1 and Ldlr were investigated. The results showed the following: (1) The abnormal serum lipid levels in hyper...

Huang(Li-Hao),Nishi(Koji),Li(Song),Ho(Thom... FEBS J 2014-06-15

...ACAT2. Both enzymes are drug targets for treating human diseases. ACAT1 is present in various cell types. It contains ni...

Cao(Xiu-zhen),Mi(Ting-yan),Li(Lin),Vermeer... Biomed Chromatogr 2014-04-07

...ACAT2, only the oxidized metabolite was detected. Using the newly developed method, YIC-C8-434, a known ACAT inhibitor, ...

Ohtawa(Masaki),Yamazaki(Hiroyuki),Ohte(Sat... Bioorg Med Chem Lett 2014-01-13

...ACAT2 inhibitory activity and higher ACAT2 isozyme selectivity than 1.

Ohtawa(Masaki),Yamazaki(Hiroyuki),Ohte(Sat... Bioorg Med Chem Lett 2014-01-13

In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carri...

Zhong(Min),Xuan(Shouyi),Wang(Ling),Hou(Xia... Bioorg Med Chem Lett 2014-01-13

...ACAT2) were developed. The whole data set was randomly split into a training set including 72 compounds and a test set i...

Shan(Changliang),Elf(Shannon),Ji(Quanjiang... Mol Cell 2014-10-21

...ACAT2 as upstream acetyltransferases of K76 and K294, respectively, and HDAC4 as the deacetylase of both sites. Expressi...