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Costunolide-induced apoptosis is caused by receptor-mediated pathway and inhi...

Kanno(Syu-ichi),Kitajima(Yasue),Kakuta(Mai... Biol Pharm Bull 2008-06-19

...FAF1), but the phosphorylation of Fas-associated death domain (FADD) at serine 194 increased from early treatment. The a...

Fas-associated factor 1 and Parkinson's disease.

Betarbet(Ranjita),Anderson(Leah R),Gearing... Neurobiol Dis 2008-12-15

...FAF1 is a Fas-binding protein implicated in apoptosis. FAF1 is the product of a gene at PARK 10 locus on chromosome 1p32...

Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumou...

Hamamura(R S),Ohyashiki(J H),Kurashina(R),... Br J Cancer 2007-12-14

...FAF1) and an oxidative stress-related gene, heme oxygenase-1(HMOX-1), known to be a target gene of hypoxia-inducible gen...

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex...

Park(Min-Young),Moon(Ji-hyun),Lee(Ki-Sung)... J Biol Chem 2007-10-24

...FAF1 reduced the level of IKKbeta activity, whereas FAF1 depletion increased the activity. These results indicate that F...

Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-li...

Kinoshita(Takeshi),Kondoh(Chiaki),Hasegawa... Int Immunol 2007-01-22

...FAF1) as a protein interacting with the pyrin domains of several PYPAFs. In these assays, FAF1 interacted strongly with ...

TRPV1 recapitulates native capsaicin receptor in sensory neurons in associati...

Kim(Sangsung),Kang(Changjoong),Shin(Chan Y... J Neurosci 2006-04-11

...FAF1 by RNA interference augments capsaicin-sensitive current in native sensory neurons. We therefore conclude that FAF1...

Microarray comparative genomic hybridization detection of chromosomal imbalan...

Hidalgo(Alfredo),Baudis(Michael),Petersen(... BMC Cancer 2006-02-27

...FAF1 (1p32.3), D9S325 (9qtel), EIF4E (eukaryotic translation initiation factor 4E, 4q24), RB1 (13q14), and DXS7132 (Xq12...

Fas-associated factor-1 mediates chemotherapeutic-induced apoptosis via death...

Park(Min-Young),Ryu(Seung-Wook),Kim(Kwang ... Int J Cancer 2005-06-07

...FAF1 is significantly reduced in gastric carcinomas. The present study demonstrates that FAF1 mediates chemotherapeutic-...

Identification of protein modulation by the synthetic retinoid CD437 in lung ...

Kim(Hyun-Jung),Lotan(Reuben) Int J Oncol 2005-07-26

...FAF1, Bid, caspase 8, cdk1, KAP, NDR, RBBP, 53BP2, Grb2, PLCgamma1, p70s6k, PP2Cdelta, PKBalpha/AKT, PDK1, and several D...

Functional and physical interactions of Faf1p, a Saccharomyces cerevisiae nuc...

Karkusiewicz(Iwona),Rempola(Bozenna),Groma... Biochem Biophys Res Commun 2004-07-20

...Faf1p, in a two hybrid interaction screen using the known nucleolar protein Krr1 as bait. The presented data indicate th...

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