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New Insights from Sum Frequency Generation Vibrational Spectroscopy into the ...

Fu(Li),Wang(Zhuguang),Batista(Victor S),Ya... J Diabetes Res 2016-10-05

...IAPP) on membrane surfaces. These applications show that SFG can provide detailed information about structures, kinetics...

Causative factors for formation of toxic islet amyloid polypeptide oligomer i...

Jeong(Hye Rin),An(Seong Soo A) Clin Interv Aging 2016-07-06

...IAPPs. Initially, pro-IAPPs undergo enzymatic reactions to produce the IAPP monomers, which can then develop into oligom...

Promotion or Inhibition of Islet Amyloid Polypeptide Aggregation by Zinc Coor...

Nedumpully-Govindan(Praveen),Yang(Ye),Ando... Biochemistry 2016-04-15

Zinc is reported to play a complex role in islet amyloid polypeptide (IAPP) aggregation, which is associated with β-cell...

Correction: Formation of lipid/peptide tubules by IAPP and temporin B on supp...

Kinnunen(Paavo K J),Domanov(Yegor A),Matti... Soft Matter 2016-03-14

...IAPP and temporin B on supported lipid membranes' by Paavo K. J. Kinnunen et al., Soft Matter, 2015, DOI: 10.1039/b92522...

Influence of a curcumin derivative on hIAPP aggregation in the absence and pr...

Pithadia(Amit S),Bhunia(Anirban),Sribalan(... Chem Commun (Camb) 2016-09-20

...IAPP. Herein, a water-soluble curcumin derivative, CurDAc, is used to investigate the mitigation of hIAPP aggregation in...

The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, an...

Gao(Mimi),Winter(Roland) J Diabetes Res 2016-02-09

...IAPP). The process of human IAPP (hIAPP) self-association, and the intermediate structures formed as well as the interac...

On the Environmental Factors Affecting the Structural and Cytotoxic Propertie...

Tomasello(Marianna Flora),Sinopoli(Alessan... J Diabetes Res 2016-02-09

...IAPP), a neuropancreatic hormone cosecreted with insulin by β-cells. IAPP is physiologically involved in glucose homeost...

Inhibition of islet amyloid polypeptide aggregation and associated cytotoxici...

Fortin(Jessica S),Benoit-Biancamano(Marie-... Can J Physiol Pharmacol 2016-10-11

...IAPP was abrogated with diclofenac and sulindac at a molar ratio of 1:5. The cytotoxic effects of pre-incubated human IA...

Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptid...

Nguyen(Phuong Trang),Andraka(Nagore),De Ca... J Diabetes Res 2016-02-09

...IAPP). Islet amyloid fibrils are virtually always associated with several biomolecules, including apolipoprotein E, meta...

Hsp72 (HSPA1A) Prevents Human Islet Amyloid Polypeptide Aggregation and Toxic...

Rosas(Paola C),Nagaraja(Ganachari M),Kaur(... PLoS One 2016-07-25

...IAPP (h-proIAPP) that is implicated in amyloid formation and β-cell toxicity. We demonstrated that h-proIAPP expression ...

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