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Zhao(Y),Ge(X),Wang(G),Zhang(Q),Geng(C),Den... Toxicol Appl Pharmacol 2026-10-00

...JAK2-STAT3 signaling pathway for focused mechanistic validation, with JAK2 as the central candidate. Molecular docking s...

Ren(H),Lai(G),Shen(W),Zhu(T),Yang(H),Fu(Y)... PLoS Negl Trop Dis 2026-07-00

...JAK2/STAT3 pathway. Concurrently, L16 inhibited PI3K/AKT signaling and reduced phosphorylation of X-linked inhibitor of ...

Longhitano(L),La Spina(E),Giallongo(S),Gia... Free Radic Biol Med 2026-07-20

...JAK2V617F-mutated cell lines (HEL, SET2) displayed respectively lower HO-1 and higher NLRP3 expression than JAK2 wild-ty...

Greenberger(S),Bar-Ilan(E),Marcu(V),Grishi... Pediatr Blood Cancer 2026-09-00

...JAK2 fusion not previously described in pcALCL. Clinical courses ranged from spontaneous regression to systemic therapy,...

Yang(Y),Zhang(Y),Zhang(Y),Su(H),Dong(H),Ji... Cell Biol Toxicol 2026-07-21

...JAK2/STAT3 signaling axis. Evidence included diminished p-JAK2 and p-STAT3, with no alteration in total JAK2 or STAT3. T...

Nakhaei(A),Taghavi(A),Aliyari(M),Afshari(A... Cancer Chemother Pharmacol 2026-07-21

...JAK2/STAT3, ERK1/2, Wnt/β-catenin, and RhoA/ROCK, as well as by inducing autophagy inhibition, ferroptosis, oxidative st...

Leiva(O),Soo(S),Liu(OC),You(V),Palmer(A),K... Int J Hematol 2026-07-21

...JAK2 driver mutations, polycythemia vera (PV) and myelofibrosis (versus essential thrombocythemia), leukocytosis, and el...

Cobb(L),Kumar(J),Roy(A),Walsh(S),Sheerin(U... BMJ Neurol Open None

...JAK2 inhibitor. This case underscores the importance of considering AGS in individuals with non-classical presentations,...

Huang(J),Wu(X),Feng(Y),Yang(A) Chin Med J (Engl) 2026-07-22

...JAK2/STAT3) pathway in TAMs, which suppressed M2 polarization and the secretion of interleukin-10 (IL-10). STC1 binds IT...

Wang(Z),Shi(J),Ye(X),Xia(X),Zhu(H),Li(Q),C... JCI Insight 2026-07-22

...JAK2/STAT5 signaling, which reciprocally maintains DTX4 transcription. This positive-feedback loop drives PPARγ expressi...