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miR-340-5p alleviates the damage effect of LPS on nucleus pulposus cells by neg…

Liu(Y),Huang(L),Gao(Z),Hou(Y),Kong(F),Hou(S)… J Orthop Surg Res 2025-07-21

...SOX4) in LDD and attempts to clarify its potential mechanism in the pathological process of LDD. A total of 88 patients ...

Integrating single-cell analysis and machine learning to identify COPD hub gene…

Liu(C),Tian(Y),Lu(R),Yue(C),Xie(Y),Zhang(T),… J Ethnopharmacol 2025-07-24

...SOX4, and ANXA1 were significantly dysregulated in both HUVECs and COPD rat models, consistent with the data analysis re...

Single-cell map of the healthy human immune system across the lifespan reveals …

Nehar-Belaid(D),Thibodeau(A),Eroglu(A),March… bioRxiv 2025-07-31

...SOX4+ populations in naïve CD4+, naïve CD8+ and γδ T cells, comprising ~30% of the naïve T cell pool. SOX4+ naïve CD4+ T...

The strategies and mechanisms of enteroviruses to evade innate immunity and the…

Yin(Y),Chi(X),Feng(Y),Jiang(Q) Front Cell Infect Microbiol 2025-00-00

...Sox4) and microRNAs (miRNAs) that inhibit TLR signaling. The review also discusses the development of vaccines against E...

Exploring novel genomic biomarkers for response and survival after neoadjuvant …

Holmsten(K),De Laere(B),Sjödahl(G),Lindberg(… ESMO Open 2025-08-00

...SOX4 gene loci, were associated with improved response and survival to NAC. Patients harboring these alterations had a h...

SOX4 mediates cancer-associated fibroblasts related radioresistance in hepatoce…

Jiang(K),Huang(B),He(S),Zhu(M),Zhao(X),Liu(M… Cell Oncol (Dordr) 2025-10-00

...SOX4 was upregulated in tumor tissues, radioresistant cells, and CAF-exposed HCC cells, correlating with poor prognosis....

SOX4 in chronic lymphocytic leukaemia: the forgotten transcription factor.

García-Muñoz(R),Alberdi-Ballina(J),Farfan-Qu… Blood Res 2025-07-04

...SOX4 expression using quantitative polymerase chain reaction (qPCR). Correlations between SOX4 levels and established pr...

Overexpression of SOX4 in MSCs inhibits cellular senescence and enhances therap…

Qi(J),Zhao(X),Gao(X),Zhu(X),Wang(J),Liu(J),W… Stem Cell Res Ther 2025-07-16

...SOX4 is a crucial regulator of cell fate and stemness. This study aims to explore the role of SOX4 in senescence of MSCs...

SOX4 promotes triple-negative breast cancer progression by promoting SRPX2 tran…

Ge(W),Shi(C),Ge(C),Zhang(S),Chen(S),Qian(J) J Mol Histol 2025-07-15

...SOX4 could bind to SRPX2 and was highly expressed in TNBC tissues and cells, down-regulation of SOX4 could inhibit the e...

Mapping chromatin interactions at melanoma susceptibility loci uncovers distant…

Thakur(R),Xu(M),Sowards(H),Yon(J),Jessop(L),… Am J Hum Genet 2025-07-03

...SOX4, as likely melanoma risk genes.

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