...SYK, with upregulation of PLCG2, collectively suggesting alterations in the TREM2-TYROBP signaling axis. In summary, thi...
...Syk) pathway with modulating disease-associated microglial transcriptional programs. This study identified HP as a stron...
...SYK-STAT1 pathway. Collectively, Co68 represents a taxane-inspired precision therapeutic that uncouples beneficial antiv...
...SYK)-phosphatidylinositol 3-kinase (PI3K), phospholipase C gamma 2 (PLCγ2), beta-catenin and transcription factor EB (TF...
...Syk, a recently proposed therapeutic target. Our results suggest that myeloid Src-family kinases are indispensable for n...
...SYK, PI3K-AKT-mTOR, and PLCγ2, leading to microglial transcriptional and metabolic reprogramming. These processes are es...
...SYK model, the transition occurs at a finite time, with the long-time phase marked by spontaneous Z_{2} symmetry breakin...
...Syk and siFos were performed in RAECs. Western diet feeding of ApoE-/- mice resulted in elevated KMT2B expression and H3...
...SYK, BTK, and JAK3. Docking analysis demonstrated favorable binding affinity, particularly to BTK. This integrative appr...
...Syk in M1 macrophage reduced these effects. Mechanistically, exosomal Syk is transferred to endothelial cells and associ...
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