Literature Search

Biar(CG),Wang(ZR),Camp(ND),Holmes(DL),Wheelo… bioRxiv 2026-01-18

...TSC2 variants are variants of uncertain significance (VUS). VUS in TSC2 have been resolved by one-at-a-time functional a...

Operto(FF),Pastorino(GMG),Charlier(B),Izzo(V… Neurol Ther 2026-04-00

...TSC2 mutations showed significantly lower IQ scores than those carrying TSC1 mutations (p < 0.001). Total parental stres...

Qi(C),Li(Y),Chen(Y),Cui(X),Wang(Q),Zhang(X),… Epilepsy Behav 2026-08-00

...TSC2 mutation, active epilepsy, and lower educational attainment were associated with greater TAND severity. TSC2 mutati...

Pal(A),Sirivela(SS),Mallick(S),Viswanathan(S) Cureus 2026-03-00

...TSC2 mutation. Tuberous sclerosis complex is associated with dysregulation of the mammalian target of rapamycin (mTOR) s...

Wu(X),He(MY),Xu(HF),He(Y),Min(XH),Zhao(QK),L… Front Pediatr None

...TSC2 mutations in 68 patients (93%), corresponding to 71 distinct mutation sites. Fourteen variants (2 in TSC1, 12 in TS...

Wang(Q),Xu(Z),Wang(J),Huang(Z),Guo(F),Xu(Z),… Hum Pathol 2026-08-00

...TSC2 mutations in 9/17. All 5 cases with condensed eosinophilic cytoplasm uniformly harbored TSC1 mutations. Analysis of...

Wang(W),Zhu(H),Chen(C),Sun(M),Wang(H),Tai(Y)… Front Immunol None

...TSC2, NFATC2, TCF7L2, TLR4, RANBP17, ITK, NEB [Chr2:152499355], NUP214, FBN2, and NEB [Chr2:152544903]). Drug-target pre...

van den Ende(NS),Smid(M),Martens(JWM),Debets… NPJ Breast Cancer 2026-05-13

...TSC2. Molecular profiling of residual disease in extensively poor responding TNBC post-NAC revealed multiple potentially...

Alsharhan(M),Alkhezi(OS),Alfayez(OM) Saudi Pharm J 2026-05-13

...TSC2 gene. The tumor size and location led to early initiation of oral everolimus at 0.06 mg/kg twice daily. Therapeutic...

Caprini(E),Scaglione(GL),Scarponi(C),Morelli… Sci Rep 2026-05-03

...TSC2) and in NF2 harbouring novel genetic alterations. Integrating our results with published datasets of AFX and PDS mu...