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The development of IL-17/IFN-γ-double producing CTLs from Tc17 cells is drive...

Satoh(Takayuki),Tajima(Masaki),Wakita(Daik... Eur J Immunol 2013-02-06

...Socs3 gene promoters. Moreover, we show that SOCS3 strongly regulates the capability of Tc17 cells to produce IL-17, in ...

Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and...

Pan(Ying),Hong(Ye),Zhang(Qing-Yu),Kong(Lin... Psychoneuroendocrinology 2013-05-20

...SOCS3) in hypothalamic arcuate nucleus (ARC) of rats. Furthermore, SOCS3 activation blocked insulin signaling pathway th...

Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulat...

van de Loo(Fons A J),Veenbergen(Sharon),va... Arthritis Rheum 2013-01-16

...SOCS3 was either reduced by small interfering RNA or enhanced by viral transduction.,The expression of SOCS-3 mRNA (but ...

The expression of suppressor of cytokine signaling 1 and 3 in fat and placent...

Kuzmicki(Mariusz),Telejko(Beata),Wawrusiew... Gynecol Endocrinol 2013-03-17

...SOCS3, interleukin-6 (IL-6), IL-6 receptor, IL-8 and leptin mRNA in paired samples of subcutaneous adipose tissue (SAT),...

The biology and mechanism of action of suppressor of cytokine signaling 3.

Babon(Jeffrey J),Nicola(Nicos A) Growth Factors 2013-01-25

...SOCS3 then inhibits JAK/STAT signaling in two distinct ways. First, SOCS3 is able to directly inhibit the catalytic acti...

Alterations of negative regulators of cytokine signalling in immunodeficiency...

Capello(Daniela),Gloghini(Annunziata),Bald... Hematol Oncol 2013-04-30

...SOCS3 epigenetic silencing were occasionally detected, whereas SOCS1 was frequently mutated in diffuse large B-cell lymp...

Increased suppressor of cytokine signaling-3 expression predicts mucosal rela...

Li(Yi),Nuij(Veerle J A A),Baars(Judith E),... Inflamm Bowel Dis 2013-08-21

...SOCS3 and its inducer p-STAT1 was shown.,SOCS3 IEC expression during remission may be useful in predicting mucosal relap...

Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen prese...

Zhang(Xin),Tao(Yazhong),Wang(Jinzhao),Garc... Eur J Immunol 2013-04-08

...SOCS3, and SOCS7 gene expression, which are associated with the inhibition of STAT1, STAT3, and ERK1/2 phosphorylation. ...

Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling t...

Gao(Shen-meng),Chen(Chi-qi),Wang(Lu-yao),H... Exp Hematol 2013-05-20

...SOCS3 by triggering the promoter-associated histone acetylation of SOCS1 and SOCS3 in K562 and HEL cell lines. Important...

Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin res...

Mashili(Fredirick),Chibalin(Alexander V),K... Diabetes 2013-04-11

...SOCS3) protein abundance was increased in skeletal muscle from T2D patients. STAT3 phosphorylation positively correlated...

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