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miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathw...

Zhou(Wenbin),Bi(Xingjie),Gao(Guojun),Sun(L... Biomed Pharmacother 0000-00-00

...JAK2 and the JAK2/STAT3 pathways was determined by Western blot. Transient transfection of miR-133b and miR-135a reduced...

Hypoxia-induced expression of cellular prion protein improves the therapeutic...

Han(Yong-Seok),Lee(Jun Hee),Yoon(Yeo Min),... Cell Death Dis 0000-00-00

...JAK2 and STAT3 activation. In addition, hypoxia preconditioning-induced PrP regulated superoxide dismutase and catalase ...

The Anticancer Properties of Herba Epimedii and Its Main Bioactive Components...

Chen(Meixia),Wu(Jinfeng),Luo(Qingli),Mo(Sh... Nutrients 0000-00-00

...JAK2-STAT3, MAPK-ERK, and PI3k-Akt-mTOR. The review is aimed to provide an overview of the current research results supp...

S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory H...

Wang(Minjun),Tang(Wenbo),Xin(Hong),Zhu(Yi ... PLoS One 0000-00-00

...JAK2/STAT3 activation. On the whole, our data reveal the inhibition of inflammatory hepcidin by SPRC, and suggest SPRC a...

CKLF-like MARVEL transmembrane domain-containing member 3 (CMTM3) inhibits th...

Li(Wujun),Zhang(Shaobo) Oncol Res 0000-00-00

...JAK2 and STAT3 in HepG2 cells. In vivo, overexpression of CMTM3 attenuated the tumor growth in Balb/c nude mice. In conc...

[Characterization of mutational pattern in patients with Ph negative myelopro...

Xing(F),Lin(Y N),Sun(Q),Qin(L),Jia(Y J),Zh... Zhonghua Bing Li Xue Za Zhi 0000-00-00

...JAK2-V617F mutation than those without JAK2-V617F or CALR (exon 9) mutation (P<0.05). The last finding was that there wa...

Results from oral gavage carcinogenicity studies of ruxolitinib in Tg.rasH2 m...

Shuey(Dana L),Oliver(Julian),Zhou(Gongfu),... Regul Toxicol Pharmacol 0000-00-00

...JAK2. It is approved for the treatment of patients with intermediate or high-risk myelofibrosis, or those with polycythe...

Evaluation of the anti-malarial activity and cytotoxicity of 2,4-diamino-pyri...

Phuangsawai(Oraphan),Beswick(Paul),Ratanab... Eur J Med Chem 0000-00-00

...JAK2 and EGFR were undertaken. We identified compound 5n and 5m as sub-micromolar inhibitors, with equivalent anti-malar...

Coexistence of lymphoproliferative and myeloproliferative neoplasms with simu...

Yang(Hai-Su) Cancer Biomark 0000-00-00

...JAK2 V617F and CALR mutations are not mutually exclusive and the actual frequency of simultaneous JAK2 V617F and CALR mu...

[Actualities in the management of primary myelofibrosis].

Simon(Zsófia),Marton(Imelda),Borbényi(Zita... Orv Hetil 0000-00-00

...JAK2 inhibitor ruxolitinib has become available in Hungary since 2015. Beside its high efficacy in spleen volume and in ...

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