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Low frequency of V617F mutation in JAK2 gene in Indian patients with hepatic ...

Rai(Praveer),Kumar(Pankaj),Mishra(Swapnil)... Indian J Gastroenterol 0000-00-00

...JAK2) gene which is highly specific for myeloproliferative disorders has been detected in 40 % to 50 % and 30 % to 35 % ...

Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney ...

Liu(Feng),Zong(Ming),Wen(Xiaofei),Li(Xuezh... Sci Rep 0000-00-00

...JAK2/STAT3 pathway and reduced the podocytes injury by decreasing the expression levels of Nephrin and Podocin. Moreover...

Co-Cr dental alloys induces cytotoxicity and inflammatory responses via activ...

Kim(Eun-Cheol),Kim(Myo-Kyoung),Leesungbok(... Dent Mater 0000-00-00

...JAK2/STAT3, p38/ERK/JNK MAPKs and NF-κB signaling pathways. Furthermore, antioxidants (resveratrol and NAC) and HO-1 inh...

Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic S...

Marusyk(Andriy),Tabassum(Doris P),Janiszew... Cancer Res 0000-00-00

...JAK2/STAT3 and hyaluronic acid. Neoadjuvant lapatinib therapy in HER2 breast tumors lead to a significant increase of ph...

The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic ...

Sanz Sanz(Arturo),Niranjan(Yashavanthi),Ha... Biochim Biophys Acta 0000-00-00

...JAK2 and causes myeloproliferative neoplasms. We conducted a detailed kinetic analysis of recombinant JAK2 tyrosine kina...

Resistance of Cancer Cells to Targeted Therapies Through the Activation of Co...

von Manstein(Viktoria),Yang(Chul Min),Rich... Curr Signal Transduct Ther 0000-00-00

...Jak2. Jak2 activity is enhanced upon SOCS2 downregulation and causes the reactivation of Stat3. A similar observation ha...

Hyperglycemia and angiotensin II cooperate to enhance collagen I deposition b...

Fiaschi(Tania),Magherini(Francesca),Gamber... Biochim Biophys Acta 0000-00-00

...JAK2/STAT3 pathway and its involvement in collagen I production by cardiac fibroblasts. We observed that the diabetic en...

Flow cytometry immunophenotypic analysis of Philadelphia-negative myeloprolif...

Ouyang(Juan),Zheng(Wenli),Shen(Qi),Goswami... Cytometry B Clin Cytom 0000-00-00

...JAK2 mutation status. Comparing with MDS, FCI abnormalities were overall less pronounced in MPN cases (p=0.001). Conclus...

JAK2 V617F detected in two B-cell chronic lymphocytic leukemia patients witho...

Yang(Yi-Ning),Qin(You-Wen),Wang(Chun) Oncol Lett 0000-00-00

...JAK2 V617F allele has rarely been evaluated in lymphoproliferative disorders. In total, 28 JAK2 V617F-positive B-cell ly...

Platycodin D inhibits tumor growth by antiangiogenic activity via blocking VE...

Luan(Xin),Gao(Yun-Ge),Guan(Ying-Yun),Xu(Ji... Toxicol Appl Pharmacol 0000-00-00

...JAK2, FAK, Src, and Akt in endothelial cells. Molecular docking simulation showed that PD formed hydrogen bonds and hydr...

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