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Jin(Zhouxiang),Zhou(Shujuan),Zhang(Yu),Ye(... Biomed Pharmacother 0000-00-00

...JAK2/STAT signaling through upregulation of SOCS1 in MM cells and patient MM cells.Importantly, we found that knockdown ...

Vranic(Semir),Ghosh(Nilanjan),Kimbrough(Je... PLoS One 0000-00-00

...JAK2/PD-L2 co-amplification using fluorescent in-situ hybridization assay (FISH). PD-L1 positivity (≥5% positive cancer ...

Darvin(Pramod),Joung(Youn Hee),Kang(Dong Y... J Cell Mol Med 0000-00-00

...Jak2/STAT1/3 and P38/STAT1/p21 pathways and induce G1-arrest and intrinsic apoptosis in breast carcinomas.

Mayfield(Jodi R),Czuchlewski(David R),Gale... Pediatr Blood Cancer 0000-00-00

...JAK2 mutation not previously described in BCP-ALL and a potential therapeutic target. Due to concern for an on-therapy r...

Yang(Chenlu),Zhang(Weijing),Wang(Longwang)... Lab Invest 0000-00-00

...JAK2/STAT3 pathway and promoted expression of genes downstream of JAK2/STAT3 in bladder cancer. This study demonstrates ...

Wang(P),Lv(H Y),Zhou(D M),Zhang(E N) Genet Mol Res 0000-00-00

...JAK2 inhibited the expression of JAK2 proteins in H1299 cells. JAK-2 overexpression effectively reversed miR-204-repress...

Floss(Doreen M),Klöcker(Tobias),Schröder(J... Mol Biol Cell 0000-00-00

...Jak2 binds to IL-23R and also to IL-12Rβ2. Receptor association of Jak2 is mediated by Box1 and Box2 motifs located with...

Nangalia(Jyoti),Grinfeld(Jacob),Green(Anth... Annu Rev Pathol 0000-00-00

...JAK2(V617F) homozygosity, the function of comutations in epigenetic regulators and spliceosome components, and how these...

Kim(Hyun-Chang),Kim(Eugene),Bae(Jung Il),L... J Neurosurg Anesthesiol 0000-00-00

...JAK2, phosphorylated JAK2 (P-JAK2), STAT3, phosphorylated STAT3 (P-STAT3), Bcl-2 (antiapoptotic protein), and Bax (proap...

Bagca(Bakiye Goker),Ozalp(Ozgun),Kurt(Cans... Tumour Biol 0000-00-00

...JAK2 inhibitory effect. In this novel study, we aimed to discover the anti-leukemic effect of ruxolitinib in K-562 human...