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Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfecte...

Vidal(Francesc),López-Dupla(Miguel),Laguno... PLoS One 2013-05-07

...SOCS3 gene polymorphism (p = 0.02 and p = 0.002, respectively). In the multivariate analysis, the associations of the SO...

STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive ...

Li(Yi),Deuring(Jasper),Peppelenbosch(Maike... Mol Med 2013-05-09

...SOCS3); hence, knowledge of the mechanisms driving mucosal SOCS3 expression may provide important clues as to rational t...

Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolon...

Chueh(Fu-Yu),Yu(Chao-Lan) Biochem Biophys Res Commun 2013-01-31

...SOCS3 and cytokine-inducible SH2 containing protein that are negative feedback regulators of STAT signaling. Moreover, e...

Sustained submicromolar H2O2 levels induce hepcidin via signal transducer and...

Millonig(Gunda),Ganzleben(Ingo),Peccerella... J Biol Chem 2013-01-07

...SOCS3 (suppressor of cytokine signaling 3), and antioxidants such as N-acetylcysteine. Glycoprotein 130 (gp130) is requi...

Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regula...

Liang(Pei),Cheng(Suk Hang),Cheng(Chi Keung... Haematologica 2013-11-25

...SOCS3, a STAT3 inhibitor, and gene silencing of SOCS3 abolished its ability to inhibit STAT3 activation, suggesting a cr...

Respiratory syncytial virus modifies microRNAs regulating host genes that aff...

Bakre(Abhijeet),Mitchell(Patricia),Coleman... J Gen Virol 2013-01-04

...SOCS3). Modulating let-7 family miRNA levels with miRNA mimics and inhibitors affected RSV replication, indicating that ...

Expression of SOCS3 throughout liver regeneration is not regulated by DNA met...

Guo(Gang),Xia(Jie),Bao(Ji),Sun(Huai-Qiang)... Hepatobiliary Pancreat Dis Int 2013-01-16

...SOCS3 gene is rich in CpG islands (CGIs). During liver regeneration initiated by partial hepatectomy, SOCS3 acts as a su...

Reduced Socs3 expression in adipose tissue protects female mice against obesi...

Palanivel(R),Fullerton(M D),Galic(S),Honey... Diabetologia 2013-02-26

...Socs3 floxed (wild-type, WT) and Socs3 aP2 (also known as Fabp4)-Cre null (Socs3 AKO) mice. Mice were maintained on eith...

SOCS1 gene transfer accelerates the transition to heart failure through the i...

Cittadini(Antonio),Monti(Maria Gaia),Iacca... Cardiovasc Res 2013-04-25

...SOCS3 was upregulated during the hypertrophic phase, SOCS1 transcript levels increased significantly between 15 and 20 w...

Maternal high-fat diet induces obesity and adrenal and thyroid dysfunction in...

Franco(J G),Fernandes(T P),Rocha(C P D),Ca... J Physiol 2013-03-25

...SOCS3 (-55%, P < 0.05) content in the arcuate nucleus, suggesting leptin resistance. HF offspring also had higher adrena...

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