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Expression of the interleukin-10 signaling pathway genes in individuals with ...

Cavalcante(Lícia Bezerra),Tanaka(Marcia Hi... J Periodontol 2013-01-08

...SOCS3, IP10, and ICAM1 mRNA in DS patients was significantly lower compared to euploid individuals with periodontal dise...

Identification of an up-regulated anti-apoptotic network in the internal thor...

Krane(Markus),Dummler(Sara),Dressen(Martin... Int J Cardiol 2012-04-09

...SOCS3 (7.2-fold, p=0.002), IER3 (4.1-fold, p=0.048), MCL-1 (2.6-fold, p=0.025) and IL-6 (17.8-fold, p=0.046) were up-reg...

Suppressor of cytokine signaling-3 is affected in T-cells from tuberculosisTB...

Jacobsen(M),Repsilber(D),Kleinsteuber(K),G... Clin Microbiol Infect 2012-03-02

...SOCS3, JAK3, interleukin-2 receptor α-chain (IL2RA), and the proto-oncogene serine/threonine protein kinase (PIM1). Clas...

Apoptosis and inflammation: role of adipokines in inflammatory bowel disease.

Ponemone(Venkatesh),Keshavarzian(Ali),Bran... Clin Transl Gastroenterol 2012-12-17

...SOCS3), Bcl-2 and Bcl-xL expression, and cytokine production was studied. In addition, the effects of globular and high-...

Suppression of cytokine signaling by SOCS3: characterization of the mode of i...

Babon(Jeffrey J),Kershaw(Nadia J),Murphy(J... Immunity 2012-04-30

...SOCS3. Surprisingly, we found that SOCS3 simultaneously bound JAK and the cytokine receptor to which it is attached, rev...

JAK's SOCS: a mechanism of inhibition.

Yoshimura(Akihiko),Yasukawa(Hideo) Immunity 2012-04-30

SOCS1 and SOCS3 are specific inhibitors for JAK tyrosine kinases. In this issue of Immunity, Babon et al. (2012) discove...

Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling ...

Ghosh(Arunava),Pahan(Kalipada) J Biol Chem 2012-11-05

...SOCS3 in glial cells. Gemfibrozil increased the expression of Socs3 mRNA and protein in mouse astroglia and microglia in...

SOCS, Inflammation, and Autoimmunity.

Yoshimura(Akihiko),Suzuki(Mayu),Sakaguchi(... Front Immunol 2012-08-23

...SOCS3 are strong inhibitors of JAKs, because these two contain kinase inhibitory region at the N-terminus. Studies using...

A dietary resveratrol-rich grape extract prevents the developing of atheroscl...

Azorín-Ortuño(María),Yañéz-Gascón(María Jo... J Agric Food Chem 2012-09-17

...SOCS3), key regulators of vascular cell responses, in peripheral mononuclear blood cells. Our results suggest that the c...

Viral-load-dependent effects of liver injury and regeneration on hepatitis B ...

Tian(Yongjun),Chen(Wen-ling),Kuo(Cheng-fu)... J Virol 2012-11-21

...SOCS3) irrespective of viral load. As both HNF3γ and Stat3 are required to activate the HBV enhancer I to stimulate HBV ...

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