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Apical constriction and invagination downstream of the canonical Wnt signalin...

Zimmerman(Sandra G),Thorpe(Lauren M),Medra... Dev Biol 2010-05-24

...APC2 APC1 double null clones in the Drosophila wing imaginal disc. APC loss leads to segregation, apical constriction, a...

Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 revea...

Zhang(Ziguo),Roe(S Mark),Diogon(Marie),Kon... J Mol Biol 2010-05-25

...Apc2 and Apc11, respectively, and a tetratricopeptide repeat (TPR) sub-complex composed of the TPR subunits Cdc16, Cdc23...

Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel di...

Dhir(Mashaal),Montgomery(Elizabeth A),Glöc... J Gastrointest Surg 2009-01-30

...APC2, SFRP1, SFRP2, SFRP4, SFRP5, DKK1, DKK3, WIF1 and LKB1, was analyzed. Methylation analysis was performed on 41 IBD ...

Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly ...

McGuinness(Barry E),Anger(Martin),Kouznets... Curr Biol 2009-06-16

...Apc2 subunit or separase. Finally, we show that Bub1's kinase domain is not required to delay APC/C activation.,We concl...

Activity of the beta-catenin phosphodestruction complex at cell-cell contacts...

Maher(Meghan T),Flozak(Annette S),Stocker(... J Cell Biol 2009-09-23

...APC2, GSK-3beta and N-terminally phosphorylated forms of beta-cat can localize to cell-cell contacts in a complex that i...

APC2 plays an essential role in axonal projections through the regulation of ...

Shintani(Takafumi),Ihara(Masaru),Tani(Sach... J Neurosci 2009-10-02

...APC2) in the development of axonal projections by using the chick retinotectal topographic projection system. APC2 is pr...

A novel role for an APC2-Diaphanous complex in regulating actin organization ...

Webb(Rebecca L),Zhou(Meng-Ning),McCartney(... Development 2009-07-22

...APC2 in this process. Colocalization of APC2 and DIA peaks during furrow extension, and localization of APC2 to furrows ...

Membrane bound axin is sufficient for Wingless signaling in Drosophila embryo...

Tolwinski(Nicholas S) Genetics 2009-05-27

...APC2 and Axin in the Wg signal transduction pathway during embryonic development of Drosophila melanogaster. I find that...

Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability s...

Kumar(Krishan),Brim(Hassan),Giardiello(Fra... Clin Cancer Res 2009-03-30

...APC2 promoters by methylation-specific PCR; and for point mutations in two oncogenes, KRAS and BRAF, by sequencing.,In o...

Promoter methylation primarily occurs in tumor cells of patients with non-sma...

De Jong(Wouter K),Verpooten(Gonda F),Krame... Anticancer Res 2009-04-16

...APC2 was determined in all samples using real-time methylation-specific PCR.,Ten patients with NSCLC and 18 non-NSCLC co...

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