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Chapman(Timothy M),Wallace(Claire),Gillen(... Bioorg Med Chem Lett 2016-05-23

A high throughput screen allowed the identification of N-hydroxyimide inhibitors of ERCC1-XPF endonuclease activity with...

Zhou(C X),Zhao(J H) Genet Mol Res 2016-01-15

Several studies have examined the association between excision repair cross-complementation group 1 (ERCC1) C8092A and E...

Zhang(Shenli),Tan(Iain B),Sapari(Nur S),Gr... J Mol Diagn 2016-01-14

...ERCC1 (rs11615), ERCC1 (rs3212986), and ERCC2 (rs13181) in 56 FFPE DNA samples. By using PCR, followed by size-based gel...

Piao(Mei Jing),Ahn(Mee Jung),Kang(Kyoung A... DNA Repair (Amst) 2016-01-21

...ERCC1), which are essential components of the NER pathway, were reduced following UVB exposure, although phloroglucinol ...

Yoshikawa(Kyohei),Noguchi(Kazuma),Nakano(Y... Int J Oncol 2016-02-02

...ERCC1, which are strongly associated with CDDP resistance, and Hippo pathway-related proteins by western blotting. Using...

Miura(John T),Xiu(Joanne),Thomas(James),Ge... Cancer Biol Ther 2016-03-01

...ERCC1 was seen in 65%, RRM1 in 62%, TS in 61% and MGMT in 45%, indicating potential benefit from epirubicin, irinotecan,...

Gao(Yang),Liu(Dong) Oral Oncol 2016-02-08

...ERCC1 expression (RR 1.19; 95%CI 1.00-1.43; P=0.06). Evidence of modest heterogeneity was found between ERCC1 expression...

Zhu(Yi),Tchkonia(Tamara),Pirtskhalava(Tama... Aging Cell 2016-04-08

...Ercc1(-/Δ) mice. In old mice, cardiac function and carotid vascular reactivity were improved 5 days after a single dose....

Popovtzer(Aron),Sarfaty(Michal),Limon(Dror... Biomed Res Int 2016-07-19

...ERCC1). Eleven patients (79%) received MP-guided treatment (2 died prior to treatment initiation, 1 opted not to be trea...

Qixing(Mao),Gaochao(Dong),Wenjie(Xia),Rong... Medicine (Baltimore) 2016-01-04

...ERCC1 rs11615 and ERCC1 rs312986 polymorphisms may be candidate pharmacogenomic factors capable of predicting the respon...