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Biochemical disorders associated with antiproliferative effect of dehydroepia...

Cheng(Mei-Ling),Shiao(Ming-Shi),Chiu(Danie... Biochem Pharmacol 2012-01-16

...MAT2A and MAT2B. SAM supplementation partially rescued cells from DHEA-induced growth stagnation. Our findings suggest t...

Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation...

Nordgren(Kendra K S),Peng(Yi),Pelleymounte... Drug Metab Dispos 2012-05-02

...MAT2A encode two distinct MAT isoforms in mammals. MAT2A is expressed in nonhepatic tissues, whereas MAT1A is expressed ...

New families of human regulatory RNA structures identified by comparative ana...

Parker(Brian J),Moltke(Ida),Roth(Adam),Was... Genome Res 2012-03-05

...MAT2A, a key metabolic gene that produces the primary human methyl donor S-adenosylmethionine; the other involving a tRN...

Inhibition of human methionine adenosyltransferase 1A transcription by coding...

Tomasi(Maria Lauda),Li(Tony W H),Li(Mei),M... J Cell Physiol 2012-03-05

...MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT). MAT1A is silenced in hepatocellular carcino...

One-carbon metabolism nutrient status and plasma S-adenosylmethionine concent...

Inoue-Choi(Maki),Nelson(Heather H),Robien(... Int J Mol Epidemiol Genet 2012-08-02

...MAT2A and MAT2B) were also determined. Linear regression and path analysis were performed to depict the directed depende...

Gene expression modifications in the liver caused by binge drinking and S-ade...

Li(Jun),Bardag-Gorce(Fawzia),Oliva(Joan),D... Genes Nutr 2012-10-02

...Mat2a, Jun, Tnfrs9, Ahcy 1, Tgfbr1 and 2, and Pcaf. At 12 h, the insulin signaling pathways were half down regulated by ...

Longevity candidate genes and their association with personality traits in th...

Luciano(Michelle),Lopez(Lorna M),de Moor(M... Am J Med Genet B Neuropsych... 2012-05-22

...MAT2A, SYNJ1, and SYNJ2) were typed in over 1,000 70-year old participants from the Lothian Birth Cohort of 1936 (LBC193...

Hypoxia induces genomic DNA demethylation through the activation of HIF-1α an...

Liu(Quanyan),Liu(Li),Zhao(Yuhong),Zhang(Ji... Mol Cancer Ther 2011-11-09

...MAT2A) maintains the homeostasis of S-adenosylmethionine (SAM), a critical marker of genomic methylation status. In this...

Silencing MAT2A gene by RNA interference inhibited cell growth and induced ap...

Liu(Quanyan),Wu(Kailang),Zhu(Ying),He(Yuem... Hepatol Res 2011-07-14

...MAT2A was found in liver cancer, suggesting that MAT2A plays an important role in facilitating cancer growth. MAT2A is a...

The X protein of hepatitis B virus inhibits apoptosis in hepatoma cells throu...

Liu(Quanyan),Chen(Jiwei),Liu(Li),Zhang(Jun... J Biol Chem 2011-07-12

...MAT2A gene promoter. In addition, overexpression of HBx or MAT2A inhibits cell apoptosis, whereas knockdown of MAT2A exp...

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