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The strategies and mechanisms of enteroviruses to evade innate immunity and the…

Yin(Y),Chi(X),Feng(Y),Jiang(Q) Front Cell Infect Microbiol 2025-00-00

...Sox4) and microRNAs (miRNAs) that inhibit TLR signaling. The review also discusses the development of vaccines against E...

Single-cell map of the healthy human immune system across the lifespan reveals …

Nehar-Belaid(D),Thibodeau(A),Eroglu(A),March… bioRxiv 2025-07-31

...SOX4+ populations in naïve CD4+, naïve CD8+ and γδ T cells, comprising ~30% of the naïve T cell pool. SOX4+ naïve CD4+ T...

SOX4 in chronic lymphocytic leukaemia: the forgotten transcription factor.

García-Muñoz(R),Alberdi-Ballina(J),Farfan-Qu… Blood Res 2025-07-04

...SOX4 expression using quantitative polymerase chain reaction (qPCR). Correlations between SOX4 levels and established pr...

Integrating single-cell analysis and machine learning to identify COPD hub gene…

Liu(C),Tian(Y),Lu(R),Yue(C),Xie(Y),Zhang(T),… J Ethnopharmacol 2025-07-24

...SOX4, and ANXA1 were significantly dysregulated in both HUVECs and COPD rat models, consistent with the data analysis re...

VEGFA and APOE regulate distinct functional states of mast cells in hepatocellu…

Lv(X),Chen(J),Abuduhailili(X),Deng(Y),Yuan(X… Int J Biol Macromol 2025-09-00

...SOX4, VEGFA), and transcriptional network analysis highlighted JUND, NF-κB, REL, and CREM as potential co-regulators of ...

miRNA-338-3p influences the liver cancer stem cells and lenvatinib resistance p…

Yuan(Y),Li(HF),Liu(ZM),Yu(LP) Sci Rep 2025-07-18

...SOX4 in liver CSCs. Moreover, miR-338-3p-associated downregulation of SOX4 prevents tumorigenesis and self-renewal in th...

Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Im…

Wan(M),Mei(J),Cai(Y),Zhou(J),Xue(N),Jiang(Y)… Adv Sci (Weinh) 2025-10-00

...SOX4 and DDR1, respectively. It is also found that IGF1R promotes tumor cell migration and invasion, as well as T cell e...

Regulatory roles of circular RNAs in Wnt and other oncogenic signaling pathways…

Khalaji(A),Nazari(Y),Pandeh(M),Farhoudian(A)… Eur J Med Res 2025-08-14

...SOX4-mediated Wnt signaling, whereas circRNF10 exhibits tumor-suppressive properties. The dual role of circRNAs as oncog...

Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellul…

Huang(H),Peng(W),Zhou(Q),Zhao(Y),Liu(L),Cui(… Cell Commun Signal 2025-08-25

...SOX4)-CTHRC1-Notch1 axis in HCC. Our study revealed that SCAFs were strongly correlated with cancer stemness in HCC. A n...

NRF2-SOX4 complex regulates PSPH in hepatocellular carcinoma and modulates M2 m…

Tsai(CN),Yu(MC),Lee(YS),Feng(KC),Wu(CH),Li(Y… Cancer Gene Ther 2025-11-00

...SOX4 complex. The SOX4-NRF2 complex directly activated Phosphoserine Phosphatase (PSPH) transcription-as revealed by luc...

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