Literature Search

Wu(X),He(MY),Xu(HF),He(Y),Min(XH),Zhao(QK),L… Front Pediatr None

...TSC2 mutations in 68 patients (93%), corresponding to 71 distinct mutation sites. Fourteen variants (2 in TSC1, 12 in TS...

Wang(Q),Xu(Z),Wang(J),Huang(Z),Guo(F),Xu(Z),… Hum Pathol 2026-08-00

...TSC2 mutations in 9/17. All 5 cases with condensed eosinophilic cytoplasm uniformly harbored TSC1 mutations. Analysis of...

Del Baldo(G),Milano(GM),Salvatore(MD),Mastro… Oncologist 2026-06-06

...TSC2 genes, resulting in constitutive mTOR signaling pathway activation, a central driver of tumorigenesis and a key the...

Yeung(MCF),Cheung(HMH),Liu(APY),Shek(TWH) Mod Pathol 2026-06-00

...TSC2 deletions and NTRK1 and ERBB3 amplifications found in a subset of cases. No pathogenic fusions were detected. Trans...

Lei(X),Lang(T),Li(P),Wu(C) Int J Mol Sci 2026-03-27

...Tsc2+/- MEFs. Mechanistically, Tsc1 or Tsc2 deletion reduced global H3K27me3, correlating with increased viability, acce...

Li(S),Zhang(N),Yin(Y) Front Oncol None

...TSC2 frameshift mutation. The patient underwent open right partial nephrectomy. Histopathology demonstrated a malignant ...

Farach(LS),Leu(C),Lal(D),Smith(AR),Montanucc… Genet Med 2026-06-00

...TSC2 may be warranted, especially as the diagnosis of TSC could mask these second neurodevelopmental disorders and knowl...

Riascos(MC),Marqusee(E),Ahmadi(S),Pappa(T),F… Endocr Pathol 2026-05-07

...TSC2 deletion and TERT copy number gain, and two (22%) with variants of uncertain significance only. Of the 12 (92%) pat...

Tahir(I),Najar(RA),Rahman(A) Cell Commun Signal 2026-05-07

...TSC2 (in addition to IκBα), and this association is reduced in thrombin-stimulated cells, suggesting a role of TSC2 in r...

Alfayez(A),Belanger(E),Cheung(S),Churg(A) Hum Pathol 2026-08-00

...TSC2) is frequently mutated in sporadic LAM, and TSC2 expression/loss can now be demonstrated by immunohistochemistry bu...