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Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus i...

Nelli(Rahul K),Dunham(Stephen P),Kuchipudi... J Virol 2012-11-05

...SOCS3), a protein suppressor of the JAK-STAT pathway, was constitutively highly expressed and transcriptionally upregula...

Silencing SOCS3 could inhibit TNF-α induced apoptosis in 3T3-L1 and mouse pre...

Zhao(Xia),Qi(Renli),Sun(Chao),Xie(Yunfei) Mol Biol Rep 2012-12-14

...SOCS3 siRNA on TNF-α induced apoptosis in 3T3-L1 preadipocytes and mouse preadipocytes. 3T3-L1 preadipocytes and mouse p...

Over-expression of leptin receptors in hypothalamic POMC neurons increases su...

Gamber(Kevin M),Huo(Lihong),Ha(Sangdeuk),H... PLoS One 2012-06-04

...Socs3) mRNA were elevated in the arcuate of HFD mice. To investigate whether increased LepRb expression per se in POMC n...

Human primary keratinocytes show restricted ability to up-regulate suppressor...

Zeitvogel(Jana),Dalpke(Alexander),Eiz-Vesp... J Biol Chem 2012-05-16

...SOCS3 is critically involved in regulating the cell-specific response to IL-27. SOCS3 was found to be significantly up-r...

The inhibition of lipopolysaccharide-induced macrophage inflammation by 4 com...

Huang(Nan),Rizshsky(Ludmila),Hauck(Catheri... Phytochemistry 2012-06-25

...SOCS3). In the current study, siRNA was used to knockdown expression of SOCS3 in RAW 264.7 macrophages and investigated ...

Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT...

Ji(Yuanyuan),Wang(Zhidong),Li(Zongfang),Li... Cell Physiol Biochem 2012-11-08

...SOCS3) expression induced by Ang II were evidently impaired by AG490. More importantly, SOCS3 siRNA remarkably reinforce...

Transcriptome-level microarray expression profiling implicates IGF-1 and Wnt ...

Ezra(Daniel G),Krell(Jonathan),Rose(Geoffr... J Clin Pathol 2012-09-13

...SOCS3 and IRS2, and downstream signalling and transcriptional regulators, such as SGK (PDK/Akt signalling) and c-JUN. Ou...

Deficient leukemia inhibitory factor signaling in muscle precursor cells from...

Broholm(Christa),Brandt(Claus),Schultz(Nin... Am J Physiol Endocrinol Met... 2012-09-28

...SOCS3 protein was upregulated in diabetic myoblasts, and knockdown of SOCS3 rescued LIF-induced gene expression in diabe...

IL-6 indirectly modulates the induction of glyceroneogenic enzymes in adipose...

Wan(Zhongxiao),Ritchie(Ian),Beaudoin(Marie... PLoS One 2012-11-28

...SOCS3 mRNA levels while decreasing PEPCK and PDK4 mRNA. AICAR decreased the expression of PDK4 and PEPCK. The activation...

Laminar regulation of STAT1 and STAT3 in black walnut extract and carbohydrat...

Leise(B S),Watts(M),Tanhoff(E),Johnson(P J... J Vet Intern Med 2012-12-31

...SOCS3 mRNA concentrations were increased at the onset of lameness in both the CHO and BWE models.,The STAT3 activation l...

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