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Isolation and sequence determination of rat islet amyloid polypeptide.

Asai(J),Nakazato(M),Kangawa(K),Matsukura(S... Biochem Biophys Res Commun 1989-11-20

...IAPP with rat IAPP. Rat IAPP was a 37-amino acid polypeptide with tyrosine amide at the C-terminus, as was the case with...

Impaired glucose tolerance is associated with increased islet amyloid polypep...

Johnson(K H),O'Brien(T D),Jordan(K),Wester... Am J Pathol 1989-10-20

...IAPP immunoreactivity with 1:15,000 dilutions of antisynthetic IAPP 7-17, whereas only one of seven normal cats had IAPP...

The complete islet amyloid polypeptide precursor is encoded by two exons.

Mosselman(S),Höppener(J W),Lips(C J),Jansz... FEBS Lett 1989-05-26

...IAPP precursor, and of the corresponding parts of the IAPP gene. Two exons, which are approx. 5 kb apart in the human ge...

Immunolocalization of islet amyloid polypeptide (IAPP) in pancreatic beta cel...

Johnson(K H),O'Brien(T D),Hayden(D W),Jord... Am J Pathol 1988-02-25

...IAPP (7-17) undecapeptide to immunohistochemically (PAP technique) document the presence of IAPP immunoreactive cells in...

An islet amyloid peptide is derived from an 89-amino acid precursor by proteo...

Sanke(T),Bell(G I),Sample(C),Rubenstein(A ... J Biol Chem 1988-12-20

...IAPP) or diabetes-associated peptide (DAP) by oligonucleotide screening of a lambda gt10 human insulinoma cDNA library. ...

Islet amyloid polypeptide-like immunoreactivity in the islet B cells of type ...

Westermark(P),Wilander(E),Westermark(G T),... Diabetologia 1988-05-16

...IAPP-immunoreactivity while A cells are unreactive. In human autopsy material, all of 11 non-diabetic individuals had IA...

Islet amyloid polypeptide: identification and chromosomal localization of the...

Mosselman(S),Höppener(J W),Zandberg(J),van... FEBS Lett 1988-12-20

...IAPP. The DNA sequence predicts that IAPP is excised from a larger precursor protein and that its carboxy-terminus is pr...

Islet amyloid in type 2 human diabetes mellitus and adult diabetic cats conta...

Westermark(P),Wernstedt(C),O'Brien(T D),Ha... Am J Pathol 1987-07-16

...IAPP origin. Although the significance of IAPP is unknown, its occurrence in pancreatic endocrine tissue and partial ide...

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic ...

Westermark(P),Wernstedt(C),Wilander(E),Hay... Proc Natl Acad Sci U S A 1987-07-08

...IAPP corresponding to positions 1-27 of human insulinoma IAPP was identical to the human IAPP except for substitutions i...

HEp-2 cell- and herpes simplex virus type 1- induced deoxythymidine kinases: ...

Wigdahl(B L),Parkhurst(J R) Antimicrob Agents Chemother 1978-12-27

...Iapp) for the alternate substrate, F(3)dThd, were 3.5 and 22.5 muM for the HEp-2 cell dTK and 63.5 and 71.0 muM for the ...

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