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Two miRNA clusters, Mir-17-92 (Mirc1) and Mir-106b-25 (Mirc3), are involved i...

Tong(Ming-Han),Mitchell(Debra Ann),McGowan... Biol Reprod 2012-09-17

...Socs3, and Stat3. The male germ cell-specific Mir-17-92 (Mirc1) knockout mice exhibit small testes, a lower number of ep...

IFNγ induces monopoiesis and inhibits neutrophil development during inflammat...

de Bruin(Alexander M),Libregts(Sten F),Val... Blood 2012-04-03

...SOCS3-dependent inhibition of STAT3 phosphorylation. These results establish a critical role for IFNγ in directing monoc...

SOCS3 deletion in B cells alters cytokine responses and germinal center outpu...

Jones(Sarah A),White(Christine A),Robb(Lor... J Immunol 2012-02-07

...SOCS3 exclusively deleted in the B cell lineage (Socs3(Δ/Δ)mb1cre(+)), we analyzed the role of SOCS3 in the response of ...

Igf2-derived intronic miR-483 promotes mouse hepatocellular carcinoma cell pr...

Ma(Ning),Li(Fuyuan),Li(Dan),Hui(Yang),Wang... Mol Cell Biochem 2012-04-27

...Socs3 expression was examined by Western blot and a reporter assay. Our results revealed that Igf2-derived intronic miR-...

Macrophages regulate expression of α1,2-fucosyltransferase genes in human end...

Nakamura(Hitomi),Jasper(Melinda J),Hull(M ... Mol Hum Reprod 2012-08-09

...SOCS3 mRNA expression was evident in epithelial cells stimulated by U937 co-culture. Several recombinant macrophage-secr...

Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependen...

Yajima(Toshitaka),Murofushi(Yoshiteru),Zho... Circulation 2012-02-07

...SOCS3 regulation on cardiac gp130 signaling remains obscure.,We generated cardiac-specific SOCS3 knockout (SOCS3 cKO) mi...

The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 in...

Serrano-Marco(L),Barroso(E),El Kochairi(I)... Diabetologia 2012-07-19

...SOCS3. Here we examined whether the peroxisome proliferator-activated receptor (PPAR)β/δ agonist GW501516 prevented acti...

IL-6 signaling SOCS critical for IL-12 host response to Toxoplasma gondii.

Mirpuri(Julie),Yarovinsky(Felix) Future Microbiol 2012-04-13

...Socs3 deletion results in prolonged IL-6 signaling measured by STAT3 phosphorylation. A role for STAT3 and SOCS3 in the ...

Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y g...

Tamboli(Robyn A),Hajri(Tahar),Jiang(Aixian... PLoS One 2012-08-27

...SOCS3, TNFAIP3, and ZFP36) relative to the RYGB non-omentectomy group. Expressions of IL6 and CCL2 were decreased at all...

Role of suppressor of cytokine signaling 3 in lipid metabolism: analysis base...

Luo(Bin),Zou(Tingting),Lu(Nan),Chai(Fan),Y... Biochem Biophys Res Commun 2012-01-27

...SOCS3 and VLCAD. We identified VLCAD as a novel SOCS3 interacting protein both in vitro and vivo, and found that SOCS3 m...

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