...IAPP fibrils but not with the higher affinity peptide, p5R. Pre-incubation with AGE-BSA abrogated binding of VC1 and p5 ...
...IAPP (amylin) and SLCO1A2 genes (P=6.2 × 10). Congruent results were found using data from participants followed up from...
...IAPP) and rat (rIAPP) islet amyloid polypeptides with several formulations of supported model lipid bilayers at the soli...
...IAPP, amylin) into toxic amyloid aggregates. The aggregation of IAPP has been directly linked to the death of pancreatic...
...IAPP) and prion106-126 (PrP106-126) fragment (JACS, 2013, 135, 13582-9). It was found that the two non-homologous peptid...
...IAPP conformational change, it is nevertheless possible to leverage foldamers to separately affect IAPP's alternative ga...
...IAPP) is a peptide central to β-cell pathology in type II diabetes. A tetraquinoline is presented that stabilizes a pre-...
...IAPP (hIAPP (Tg/o)) and cultured for 8 days following cholesterol loading, microRNA-33 overexpression (to reduce ABCA1 e...
...IAPP), which has been associated with type II diabetes, and prepared IAPP modified with the fluorescence dye, Alexa532. ...
...IAPP contributes to pancreatic β-cell death in diabetes, but the nature of toxic IAPP species remains elusive. Using con...
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