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The pattern recognition reagents RAGE VC1 and peptide p5 share common binding...

Kennel(Stephen J),Williams(Angela),Stuckey... Amyloid 0000-00-00

...IAPP fibrils but not with the higher affinity peptide, p5R. Pre-incubation with AGE-BSA abrogated binding of VC1 and p5 ...

Genome-wide interaction study of brain beta-amyloid burden and cognitive impa...

Roostaei(T),Nazeri(A),Felsky(D),De Jager(P... Mol Psychiatry 0000-00-00

...IAPP (amylin) and SLCO1A2 genes (P=6.2 × 10). Congruent results were found using data from participants followed up from...

Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Pho...

Junghans(Ann),Watkins(Erik B),Majewski(Jar... Langmuir 0000-00-00

...IAPP) and rat (rIAPP) islet amyloid polypeptides with several formulations of supported model lipid bilayers at the soli...

Identification of Plant Extracts that Inhibit the Formation of Diabetes-Linke...

Fuentes(Ana Lucia),Hennessy(Kathleen),Pasc... J Herb Med 0000-00-00

...IAPP, amylin) into toxic amyloid aggregates. The aggregation of IAPP has been directly linked to the death of pancreatic...

Replica exchange molecular dynamics simulation of cross-fibrillation of IAPP ...

Chua(Khi Pin),Chew(Lock Yue),Mu(Yuguang) Proteins 0000-00-00

...IAPP) and prion106-126 (PrP106-126) fragment (JACS, 2013, 135, 13582-9). It was found that the two non-homologous peptid...

Foldamer scaffolds suggest distinct structures are associated with alternativ...

Kumar(Sunil),Birol(Melissa),Miranker(Andre... Chem Commun (Camb) 0000-00-00

...IAPP conformational change, it is nevertheless possible to leverage foldamers to separately affect IAPP's alternative ga...

Foldamer-mediated manipulation of a pre-amyloid toxin.

Kumar(Sunil),Birol(Melissa),Schlamadinger(... Nat Commun 0000-00-00

...IAPP) is a peptide central to β-cell pathology in type II diabetes. A tetraquinoline is presented that stabilizes a pre-...

ABCA1 deficiency and cellular cholesterol accumulation increases islet amyloi...

Wijesekara(Nadeeja),Kaur(Achint),Westwell-... Diabetologia 0000-00-00

...IAPP (hIAPP (Tg/o)) and cultured for 8 days following cholesterol loading, microRNA-33 overexpression (to reduce ABCA1 e...

Elongation of amyloid fibrils through lateral binding of monomers revealed by...

Yagi(Hisashi),Abe(Yuki),Takayanagi(Naoto),... Biochim Biophys Acta 0000-00-00

...IAPP), which has been associated with type II diabetes, and prepared IAPP modified with the fluorescence dye, Alexa532. ...

Time-resolved studies define the nature of toxic IAPP intermediates, providin...

Abedini(Andisheh),Plesner(Annette),Cao(Pin... Elife 0000-00-00

...IAPP contributes to pancreatic β-cell death in diabetes, but the nature of toxic IAPP species remains elusive. Using con...

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