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A novel role for an APC2-Diaphanous complex in regulating actin organization ...

Webb(Rebecca L),Zhou(Meng-Ning),McCartney(... Development 2009-07-22

...APC2 in this process. Colocalization of APC2 and DIA peaks during furrow extension, and localization of APC2 to furrows ...

Adenomatous polyposis coli is present near the minimal level required for acc...

Benchabane(Hassina),Hughes(Edward G),Takac... Development 2008-06-02

...Apc2. Unexpectedly, a less than twofold reduction in total Apc activity, achieved by loss of Apc2, decreases the effecti...

Akt regulates centrosome migration and spindle orientation in the early Droso...

Buttrick(Graham J),Beaumont(Luke M A),Leit... J Cell Biol 2008-03-18

...APC2/E-APC and the MT + Tip protein EB1. We also show that reduced levels of Akt result in mislocalization of APC2 in po...

The tissue effect of second generation argon plasma coagulation (VIO APC) in ...

Manner(Hendrik),May(Andrea),Faerber(Michae... Acta Gastroenterol Belg 2008-04-10

...APC2, Erbe, Germany), standard APC (APC 300/Erbotom ICC 200, Erbe) and Nd:YAG laser (KTP/YAG XP 800; Laserscope, San Jos...

p53 downstream target DDA3 is a novel microtubule-associated protein that int...

Hsieh(P-C),Chang(J-C),Sun(W-T),Hsieh(S-C),... Oncogene 2007-09-06

...APC2), a homolog of the tumor suppressor APC, which is a component of the beta-catenin destruction complex. Ectopic expr...

HER4 D-box sequences regulate mitotic progression and degradation of the nucl...

Strunk(Karen E),Husted(Carty),Miraglia(Lea... Cancer Res 2007-08-21

...APC2) using short interfering RNA knockdown impaired s80(HER4) degradation. Mutation of the s80(HER4) D-box sequence sta...

Cell cycle-dependent expression of centrosomal ninein-like protein in human c...

Wang(Yang),Zhan(Qimin) J Biol Chem 2007-09-25

...APC2 or Cdc27 subunits and is ubiquitinated. Following treatment with proteasome inhibitors, its protein level is elevat...

Novel roles for APC family members and Wingless/Wnt signaling during Drosophi...

Hayden(Melissa A),Akong(Kathryn),Peifer(Mark) Dev Biol 2007-10-19

...APC2 in clones of cells in the Drosophila larval optic lobe. We focused on the medulla, where epithelial neural progenit...

High-throughput screening for inhibitors of the e3 ubiquitin ligase APC.

Huang(Jianing),Sheung(Julie),Dong(Guoqiang... Methods Enzymol 2007-05-31

...APC2), and Flag-ubiquitin has been established and used to screen for small molecule inhibitors of APC E3 ligase activit...

Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated...

Jubb(A M),Chalasani(S),Frantz(G D),Smits(R... Oncogene 2006-07-24

...APC2, or transiently transfected with short-interfering RNA (siRNA) against beta-catenin showed a significant downregula...

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