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Increased expression of cathepsin L: a novel independent prognostic marker of...

Ruan(Jian),Zheng(Hang),Fu(Wenguang),Zhao(P... PLoS One 2015-07-02

...CTSL expression was significantly shorter than the low CTSL expression group. high CTSL expression was significantly cor...

Targeted and heat-triggered doxorubicin delivery to tumors by dual targeted c...

Dicheva(Bilyana M),ten Hagen(Timo L M),Sch... J Control Release 2015-08-10

...CTSL upon an external heat-trigger delivered 3-fold higher Dox quantity to tumors than TSL. Dox-CTSL bound specifically ...

Expression and regulation of avian cathepsin L in the oviduct during molting.

Bae(Seung-Min),Lim(Whasun),Jeong(Wooyoung)... Gen Comp Endocrinol 2015-04-23

...CTSL in avian species. In the present study, the expression of CTSL was investigated in the oviduct of hens during regre...

Transcriptional profiles of peripheral blood leukocytes identify patients wit...

Subimerb(Chutima),Wongkham(Chaisiri),Khunt... Asian Pac J Cancer Prev 2015-05-25

...CTSL and SERPINB2) computed as "prognostic index" was found to be an independent and statistically significant predictor...

Biomechanical loading modulates proinflammatory and bone resorptive mediators...

Nogueira(Andressa Vilas Boas),Nokhbehsaim(... Mediators Inflamm 2015-02-12

...CTSL) and high (CTSH) magnitudes for 1 and 3 days. Synthesis of cyclooxygenase-2 (COX2) and prostaglandin E2 (PGE2) was ...

Cathepsin L is involved in proliferation and invasion of ovarian cancer cells...

Zhang(Luosheng),Wei(Lixia),Shen(Guanzhu),H... Mol Med Rep 2015-06-26

...CTSL in the development of OC. In this study, RNA interference with a CTSL small hairpin RNA (CTSL-shRNA), and a plasmid...

Protective role of cathepsin L in mouse skin carcinogenesis.

Benavides(Fernando),Perez(Carlos),Blando(J... Mol Carcinog 2014-10-06

...CTSL is increased in papillomas and squamous cell carcinomas (SCC). We also carried out carcinogenesis studies using Cts...

Double deficiency of cathepsins B and L results in massive secretome alterati...

Tholen(Stefan),Biniossek(Martin L),Gansz(M... Cell Mol Life Sci 2014-04-08

...Ctsl. Previous studies showed a strong impact of Ctsl on the MEF secretome. Here we show that Ctsb alone has only a mild...

The antimalarial amodiaquine causes autophagic-lysosomal and proliferative bl...

Qiao(Shuxi),Tao(Shasha),Rojo de la Vega(Mo... Autophagy 2014-09-02

...CTSL, CTSD). AQ-treatment was associated with early induction of energy crisis (ATP depletion) and sensitized melanoma c...

Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells.

Croke(Monica),Neumann(Martin A),Grotsky(Da... Cell Cycle 2014-07-22

...CTSL)-mediated degradation of 53BP1. Accordingly, growth-arrested cells do not form BRCA1 or 53BP1 ionizing radiation-in...

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