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Oskarsson(Marie E),Paulsson(Johan F),Schul... Am J Pathol 2015-11-25

...IAPP), proIAPP, or amyloid-beta (Aβ) into human IAPP transgenic mice triggered IAPP amyloid formation in pancreas in 5 o...

Lolicato(Fabio),Raudino(Antonio),Milardi(D... Eur J Med Chem 2015-11-24

...IAPP aggregation. However, the mechanism by which resveratrol inhibits IAPP aggregation is still far from complete eluci...

Nedumpully-Govindan(Praveen),Ding(Feng) Sci Rep 2015-11-25

...IAPP with different insulin oligomers and compared with IAPP homodimer formation. We found that IAPP binding with insuli...

Tu(Ling-Hsien),Young(Lydia M),Wong(Amy G),... Biochemistry 2015-04-14

...IAPP. In this study, we use a series of IAPP variants to examine possible interactions between resveratrol and IAPP. Flu...

Xiao(Jinfeng),Li(Xiaotong),Zhao(Xin),He(Bi... Zhonghua Nei Ke Za Zhi 2015-10-22

...IAPP incubation, respectively. (2) Glibenclamide-stimulated calcium influx was dose dependently inhibited by IAPP from 1...

Patel(Hiren R),Pithadia(Amit S),Brender(Je... J Phys Chem Lett 2015-08-19

...IAPP is closely involved. Intermediate IAPP aggregates are highly toxic to islet cells, but lack of structural knowledge...

Morriss-Andrews(Alex),Shea(Joan-Emma) J Phys Chem Lett 2015-08-19

...IAPP) as a case study. We review salient open questions where simulations can make an impact, discuss the successes and ...

Younan(Nadine D),Viles(John H) Biochemistry 2015-10-05

...IAPP) associated with type II diabetes. Using a well-plate reader, we show all three fluorophores can report the kinetic...

Westwell-Roper(Clara Y),Chehroudi(Cyrus A)... Diabetologia 2015-12-22

...IAPP) to form amyloid contributes to beta cell dysfunction in type 2 diabetes. Human but not non-amyloidogenic rodent IA...

Rubio(Marisa A),Schlamadinger(Diana E),Whi... Biochemistry 2015-04-17

...IAPP self-assembly in solution and affect IAPP-induced toxicity in insulin-secreting cells.