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Transcriptomic responses and molecular mechanisms of glucagon-regulated gluco...

Zhang(T),Wang(H),Xiao(T),Yang(M),Zhang(W) Front Physiol None

...SOCS3 and TRIB3 were upregulated and may serve as key regulators linking glucagon and insulin signaling. Functional expe...

Gut microbiota induces dysspermatogenesis via microbial-derived phenylacetylg...

Tang(J),Wang(L),Yang(Z),Song(Y),Wu(S),Lian... Microbiome 2026-04-21

...SOCS3 upregulation, and STAT5B phosphorylation suppression; p-STAT5B with transcriptional activation function is reduced...

Sodium Houttuyfonate improves cognitive impairment in mice after chronic slee...

Li(R),Zhu(Y),Wei(H),Yu(M),Xu(Y) Int Immunopharmacol 2026-07-01

...SOCS3/STAT3 pathway, and si-SOCS3 treatment significantly diminished these anti-inflammatory effects of SH, confirming t...

LOXL4 drives radiotherapy resistance and immunosuppression in glioma by targe...

Du(G),Ding(Z),Hou(J),Su(Q),Li(Q),Xia(X),Ya... Int Immunopharmacol 2026-08-01

...SOCS3). This relieves SOCS3-mediated inhibition of JAK2, leading to sustained STAT3 activation. Consequently, this axis ...

Targeted peptide-modified M2 exosomes drug delivery system for the targeted r...

Zou(JR),Yang(D),Zhang(CM),Zhang(L),Zhang(H... Br J Pharmacol 2026-08-00

...SOCS3 and promoting tissue barrier reconstruction. Gene interaction network identified Spib-Pou2f1-Aicda/Tnfrsf4 as the ...

Integrated immune, apoptotic and mitochondrial gene dysregulation in Long COV...

Ali(YH),Abbas(U),Khalid(MU),Ahmed(I),Hussa... Sci Rep 2026-05-15

...SOCS3, HIF-1α, OAS1, MAVS, IFN-α, IFN-γ), anti-apoptotic markers (MCL1, BCL-2, XIAP, LIVIN), cell cycle kinases (CDK4, C...

Ketone Body β-Hydroxybutyrate Enhances Hypothalamic Leptin and Insulin Respon...

Xu(R),Takahashi(N),Kaneko(K) Nutrients 2026-02-10

...SOCS3 and TNFα expression and increased POMC expression. Furthermore, chronic ICV administration of β-HB from the onset ...

Houpu Sanwu decoction alleviates rat intraperitoneal adhesion by regulating m...

Liu(M),Chen(Q),Cui(Y),Wang(T),Li(Q),Wu(Z),... Tissue Cell 2026-06-00

...SOCS3/JAK2/STAT1 pathway, and promote the polarization of macrophages toward M2. These results suggest that Hopu Sanwu d...

Identification of Novel Biomarkers for Crohn's Disease Through the Integratio...

Chen(L),Hua(J) FASEB J 2026-03-15

...SOCS3, PF4, and IL1R1), which demonstrated robust diagnostic performance for CD. These biomarkers were correlated with t...

m6A-dependent translation of circPICALM encodes a novel metastasis-promoting ...

Li(H),Wang(S),Dai(F),Liu(H),Zhang(C),Liu(M... Mol Cancer 2026-03-04

...SOCS3 and STAT3 by directly binding to both proteins. This interference alleviates SOCS3-mediated suppression of JAK act...

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