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TP53 BRCA1 CRISPR single-cell cancer

Boeck(S H),Vehling-Kaiser(U),Waldschmidt(D... J Clin Oncol 0000-00-00

...KRAS mutation (mut). Pts with KRAS wildtype (wt, n=53) had an improved OS (wt: 8.0 mo vs. mut: 6.6 mo; HR 1.62, p=0.011)...

Goss(G D),Lorimer(I),Tsao(M S),O'Callaghan... J Clin Oncol 0000-00-00

...KRAS and EGFR copy are available on 350 and 348 pts respectively. KRAS mutations were neither prognostic HR 1.12 (95% C....

Mitchell(E P),Lacouture(M),Shearer(H),Iann... J Clin Oncol 0000-00-00

...KRAS evaluable pts, 49 (56%) pts had WT KRAS and 38 (44%) pts had MT KRAS. Efficacy and safety are shown. Mean (SD) chan...

Junemann(Alexander),Filić(Vedrana),Winterh... Proc Natl Acad Sci U S A 0000-00-00

...KRas.

Patel(Snehal G),Carty(Sally E),McCoy(Kelly... Surgery 0000-00-00

...KRAS (64%; P = .05). No preoperative variables were associated with malignancy including age (P = .07), sex (P = .49), R...

da Silva Amancio(Alice Muglia Thomaz),da C... Hum Pathol 0000-00-00

...KRAS, and BRAF. Protein overexpression was noted in nearly half of the cases and was associated with cancer recurrence (...

Ooi(Akishi),Oyama(Takeru),Nakamura(Ritsuko... Hum Pathol 0000-00-00

...KRAS in single cancer nuclei. The observation that cells with G1-S regulatory gene amplification contained clonal subpop...

Mirra(Paola),Nigro(Cecilia),Prevenzano(Imm... Biochim Biophys Acta 0000-00-00

...KRAS are increased by both MGO and miR-190a inhibitor, and these levels are reduced by miR-190a mimic transfection. Inte...

Yu(Xianjun),Liang(Chen),Qin(Yi),Zhang(Bo),... Mol Cancer Res 0000-00-00

...KRAS, and their expression strongly correlated with each other. Mechanistically, the KRAS/ERK axis induced up-regulation...

Sorber(Laure),Zwaenepoel(Karen),Deschoolme... J Mol Diagn 0000-00-00

...KRAS mutated cell-free tumor DNA (ctDNA). Digital droplet PCR was used to quantify the total cfDNA concentration as well...

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